Rapid elimination of invasive insect agricultural pest outbreaks by tackling them with Sterile Insect Technique programs

Project Information

REACT

Grant agreement ID: 101059523

DOI

10.3030/101059523

EC signature date 3 June 2022

Start date 1 November 2022

End date 30 April 2027

Funded under

• Food, Bioeconomy Natural Resources, Agriculture and Environment

Total cost

€ 6 653 075,00

EU contribution

€ 6 653 072,00

Coordinated by

JUSTUS-LIEBIG-UNIVERSITAET GIESSEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (3)

D7.3_Data management plan (DMP) developed (* = periodic updates in m18, m36)

Data management plan (DMP) developed (due date month 6, with periodic updates in m18, m36)

D7.3_Data management plan (DMP) developed, periodic update 1

D7.3_Data management plan (DMP) developed, periodic updates in m18

D7.3_Data management plan (DMP) developed, periodic update 2

D7.3_Data management plan (DMP) developed, periodic updates in m36

Websites, patent fillings, videos etc. (1)

D7.1_Project website developed and setup

Project website developed and setup

Publications

Peer reviewed articles (24)

Development of gene-edited Zeugodacus tau and Bactrocera zonata white pupae lines in support of sterile insect technique applications

Author(s): Zhi Gong, Chrysanthi Ioannidou, Marc F. Schetelig, Elena Drosopoulou, Kostas Bourtzis
Published in: Entomologia Generalis, Issue 45, 2025, ISSN 0171-8177
Publisher: Schweizerbart
DOI: 10.1127/ENTOMOLOGIA/3833

CRISPR/Cas9‐mediated mutagenesis of the <i>white‐eye</i> gene in the tephritid pest <i>Bactrocera zonata</i>

Author(s): Albert Nazarov, Tamir Partosh, Flavia Krsticevic, Dimitris Rallis, Yael Arien, Guy Ostrovsky, Reut Madar Kramer, Eyal Halon, Alfred M. Handler, Simon W. Baxter, Yoav Gazit, Kostas D. Mathiopoulos, Gur
Published in: Insect Science, 2025, ISSN 1672-9609
Publisher: Wiley
DOI: 10.1111/1744-7917.70150

Improved piggyBac Transformation with Capped Transposase mRNA in Pest Insects

Author(s): Irina Häcker, Tanja Rehling, Henrik Schlosser, Daniela Mayorga-Ch, Mara Heilig, Ying Yan, Peter A. Armbruster, Marc F. Schetelig
Published in: International Journal of Molecular Sciences, Issue 24, 2023, ISSN 1422-0067
Publisher: MDPI AG
DOI: 10.3390/IJMS242015155

Evolutionary dynamics of type VI secretion systems in fruit fly-associated Enterobacter

Author(s): Naima Bel Mokhtar, Panagiota Stathopoulou, Elias Asimakis, Antonios Augustinos, Julieta Salgueiro, Malini Alleck, Preeaduth Sookar, Óscar Dembilio, Diego F. Segura, George Tsiamis
Published in: Frontiers in Microbiology, Issue 17, 2026, ISSN 1664-302X
Publisher: Frontiers Media SA
DOI: 10.3389/FMICB.2026.1755534

Biology, ecology and invasiveness of the Mediterranean fruit fly, Ceratitis capitata: a review

Author(s): Giunti, Giulia; Benelli, Giovanni; Campolo, Orlando; Canale, Angelo; Kapranas, Apostolos; Liedo, Pablo; De Meyer, Marc; Nestel, David; Ruiu, Luca; Scolari, Francesca; Wang, Xingeng; Papadopoulos, Nikos T.
Published in: Entomologia Generalis, Issue 43, 2023, ISSN 0171-8177
Publisher: Schweizerbart Science Publishers
DOI: 10.1127/entomologia/2023/2135

<i>Enterobacter</i> -based dietary supplements in both larvae and adult diet affect thermal response of sterile males

Author(s): Georgia Papadogiorgou, Panagiota Koskinioti, Vasilis Rodovitis, Gerasimos Giannatos, Antonios Augustinos, George Tsiamis, Nikos Papadopoulos
Published in: Bulletin of Entomological Research, Issue 116, 2026, ISSN 0007-4853
Publisher: Cambridge University Press (CUP)
DOI: 10.1017/S0007485326101035

Pathogen-Mediated Alterations of Insect Chemical Communication: From Pheromones to Behavior

Author(s): Andrea Moyano, Anna Cleta Croce, Francesca Scolari
Published in: Pathogens, Issue 12, 2023, ISSN 2076-0817
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens12111350

Mosquito sex separation using complementation of selectable traits and engineered neo-sex chromosomes

Author(s): Doron S. Y. Zaada, Or Toren, Flavia Krsticevic, Daniella A. Haber, Denys Gildman, Noam Galpaz, Irina Häcker, Marc F. Schetelig, Eric Marois, Yael Arien & Philippos A. Papathanos
Published in: Nature Communications, 2025, ISSN 2041-1723
Publisher: Springer
DOI: 10.1038/S41467-025-66940-0

Detection of sex chromosomes in Tephritid pests using R-CQ and KAMY, two computational methods to support generic pest management applications

Author(s): Dimitris Rallis, Konstantina T. Tsoumani, Flavia Krsticevic, Philippos Aris Papathanos, Georgia Gouvi, Angela Meccariello, Kostas D. Mathiopoulos, Alexie Papanicolaou
Published in: Insect Science, 2025, ISSN 1672-9609
Publisher: Wiley, Institute of Zoology, Chinese Academy of Sciences
DOI: 10.1111/1744-7917.70194

Applying convolutional neural networks to X-ray images to improve postharvest detection of fruit fly infestation

Author(s): Francesca Scolari, Leani Serfontein, Wayne Kirkman, Sean Moore, Jakobus Hoffman, Lunga Bam, Andrea Moyano, Guy F. Sutton, Claudio Pezzoni, Grzegorz J. Możdżyński, Dario Pescini, Anna Sandionigi, Aruna Manrakhan
Published in: Postharvest Biology and Technology, Issue 243, 2026, ISSN 0925-5214
Publisher: Elsevier BV
DOI: 10.1016/J.POSTHARVBIO.2026.114707

Entomologia Generalis

Author(s): Peng, Peng-Shuai; Häcker, Irina; Gao, Jing-Han; Rehling, Tanja; Petermann, Sarah; Wang, Jin-Jun; Schetelig, Marc F.; Jiang, Hong-Bo; Yan, Ying
Published in: Entomologia Generalis, 2025, ISSN 0171-8177
Publisher: E. Schweizerbart'sche Verlagsbuchhandlung
DOI: 10.1127/ENTOMOLOGIA/3635

Genetic engineering for SIT application: a fruit fly‐focused review

Author(s): Serafima Davydova, Danheng Yu, Angela Meccariello
Published in: Insect Science, 2025, ISSN 1672-9609
Publisher: Wiley
DOI: 10.1111/1744-7917.70038

Genomic Tracing Reveals Multiple Independent Occurrences of Bactrocera dorsalis in Belgium

Author(s): Sam Vanbergen, Pablo Deschepper, Jan Van Autreve, Vera Huyshauwer, Massimiliano Virgilio, Jochem Bonte, Wannes Dermauw
Published in: Insects, Issue 16, 2025, ISSN 2075-4450
Publisher: MDPI AG
DOI: 10.3390/INSECTS16121271

The fallacy of the integrated pest management paradigm and the need for its OFF seasonal shift in the management of tropical fruit flies (Diptera: Tephritidae): The case of Ceratitis capitata

Author(s): Slawomir A. Lux, Andrea Sciarretta, Nikos T. Papadopoulos
Published in: Current Research in Insect Science, Issue 8, 2025, ISSN 2666-5158
Publisher: Elsevier BV
DOI: 10.1016/J.CRIS.2025.100116

Management of the Mediterranean fruit fly, Ceratitis capitata: past, present, and future

Author(s): Giunti, Giulia; Benelli, Giovanni; Campolo, Orlando; Canale, Angelo; Kapranas, Apostolos; Liedo, Pablo; De Meyer, Marc; Nestel, David; Ruiu, Luca; Scolari, Francesca; Wang, Xingeng; Papadopoulos, Nikos T.
Published in: Entomologia Generalis, Issue 43, 2023, ISSN 0171-8177
Publisher: Schweizerbart Science Publishers
DOI: 10.1127/entomologia/2023/2136

A self-limiting sterile insect technique alternative for Ceratitis capitata

Author(s): Serafima Davydova, Junru Liu, Yiran Liu, Kavya Prince, Jonathan Mann, Nikolay P. Kandul, W. Evan Braswell, Jackson Champer, Omar S. Akbari, Angela Meccariello
Published in: BMC Biology, Issue 23, 2025, ISSN 1741-7007
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S12915-025-02201-2

CRISPR/Cas9-based white pupae mutant lines in Bactrocera spp. for sterile insect technique applications

Author(s): Chrysanthi Ioannidou, Maria-Eleni Gregoriou, Marc F. Schetelig, Elena Drosopoulou, Kostas D. Mathiopoulos, Kostas Bourtzis
Published in: Insect Science, 2025, ISSN 1672-9609
Publisher: Wiley, Institute of Zoology, Chinese Academy of Sciences
DOI: 10.1111/1744-7917.70190

Neoclassical development of genetic sexing strains for insect pest and disease vector control

Author(s): Giovanni Petrucci, Maria‐Eleni Gregoriou, Philippos Aris Papathanos, Marc F. Schetelig, Zhijian Tu, Kostas Bourtzis
Published in: Insect Science, 2025, ISSN 1672-9609
Publisher: Wiley
DOI: 10.1111/1744-7917.70192

Functional validation of a <i>white pupae</i> minimal gene construct in <i>Ceratitis capitata</i> (Diptera: Tephritidae)

Author(s): Prates, Lucas; Aumann, Roswitha A.; Sievers, Inga; Rehling, Tanja; Schetelig, Prof. Dr. Marc F.
Published in: Insect Science, 2025, ISSN 1744-7917
Publisher: Wiley
DOI: 10.1111/1744-7917.70058

Decoding and engineering temperature-sensitive lethality in <i>Ceratitis capitata</i> for pest control

Author(s): Roswitha A. Aumann; Georgia Gouvi; Maria-Eleni Gregoriou; Tanja Rehling; Germano Sollazzo; Kostas Bourtzis; Marc F. Schetelig
Published in: Proceedings of the National Academy of Sciences, 2025, ISSN 1091-6490
Publisher: National Academy of Sciences (NAS)
DOI: 10.1073/PNAS.2503604122

Adaptation of the PESTonFARM Model to Support Decision-Making and Planning of Local Implementation of the Sterile Insect Technique in the Control of Ceratitis capitata Flies (Diptera: Tephritidae)

Author(s): Slawomir Antoni Lux; Marco Colacci
Published in: Applied Sciences, Issue 15(12), 2025, ISSN 2076-3417
Publisher: MDPI
DOI: 10.3390/APP15126694

<i>Enterobacter</i> supplement and ambient conditions determine the performance of sterile male Mediterranean fruit flies

Author(s): Panagiota Koskinioti, Georgia D. Papadogiorgou, Vasilis G. Rodovitis, Paraschos N. Prekas, Eleftheria‐Maria D. Bali, Gerasimos Giannatos, George C. Kagadis, Antonios A. Augustinos, George Tsiamis, Nikos T. Papadopoulos
Published in: Physiological Entomology, 2026, ISSN 0307-6962
Publisher: Wiley
DOI: 10.1111/PHEN.70054

Generating cisgenic sexing strains in insect pests

Author(s): Serafima Davydova, Junru Liu, Nikolay P. Kandul, Igor Antoshechkin, Jonathan Mann, W. Evan Braswell, Omar S. Akbari, Angela Meccariello
Published in: Communications Biology, Issue 9, 2026, ISSN 2399-3642
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S42003-026-09624-9

Navigating uncertainty in museum workflows: genomic data mining and curation of the Diptera collections hosted at RMCA

Author(s): Lore Esselens; Pia Addison; Jacqueline Bakengesa; Luis Bota; Laura Canhanga; Domingos Cugala; Beatriz Daniel; Marc De Meyer; Hélène Delatte; Jean-Marc Herpers; Kurt Jordaens; Sija Kabota; Abdul Kudr
Published in: Biodiversity Data Journal, 2025, ISSN 1314-2828
Publisher: Pensoft Publishers
DOI: 10.3897/BDJ.13.E157274

Book chapters (2)

Genetic sexing for Sterile Insect Technique programs

Author(s): Marc F. Schetelig, Kostas Bourtzis
Published in: Comprehensive Molecular Insect Science, 2026
Publisher: Elsevier
DOI: 10.1016/B978-0-323-95424-2.00054-6

The evolution of the sterile insect technique from concept to global application

Author(s): Kostas Bourtzis, Marc F. Schetelig, Walther Enkerlin, Rui Pereira
Published in: Comprehensive Molecular Insect Science, 2026
Publisher: Elsevier
DOI: 10.1016/B978-0-323-95424-2.00064-9