Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals widely used for more than 60 years to make plastics, firefighting foams, and lubricants and help create stain-resistant, waterproof, and nonstick products. However, they ended up in the environment and can now be found in the soil, water, and sediment, accumulated in human bodies, and represent a worldwide challenge. Thus, to the broader audience, they are known as chemicals which cause "forever pollution". The Serbian national chemicals legislation recognises these chemicals, but none of the existing scientific or governmental institutions analysed these compounds before the beginning of the PFAStwin project. In addition, a solution to the challenge of remediation of polluted environment is not in sight, not only in Serbia but worldwide. Based on a number of publications in peer-reviewed journals, a number of international projects, and many students, the University of Belgrade-Faculty of Chemistry (UBFC) is one of the leading scientific institutions in Serbia. PFAStwin project aims to enhance networking activities between UBFC and two top-class counterparts, who are leaders in PFAS analysis (IQOG-CSIC from Spain) and innovative (bio)remediation of emerging pollutants (BRGM from France). In addition, this project focuses on strengthening the research management capacities and administrative skills of the Grant Office from UBFC. This is conducted through the development of a scientific strategy for dealing with PFAS (WP1), knowledge transfer in the field of analysis and (bio)remediation of emerging pollutants (WP2), networking and promoting joint research integrating creativity and developing new approaches for PFAS remediation (WP3), capacity building of the UBFC Grant Office (WP4), and through dissemination, exploitation and communication (WP5). The expected impact of PFAStwin is to enhance the reputation, research and administrative profile, and networking channels of UBFC and improve its capability to compete successfully for national, EU, and international research funding while simultaneously benefiting partner institutions through new contacts, skills, and collaborations.