Project description
New solutions to improve plant stress responses against pathogens
How do plants respond to stress? The answer to this question is important in efforts to promote agriculture in ways that preserve biodiversity without increasing arable land surface. With support from the Marie Skłodowska-Curie Actions (MSCA), the DEMEtRA project will combine biochemical and imaging techniques to obtain a deep characterisation of the metabolic regulation of plant signalling in response to bacterial pathogens. This project will lead to a thorough characterisation of the NADP/H production mechanism and of the perturbations of long-distance signalling caused by a shortage of NADP/H. This will enable the design of new solutions to improve plant stress responses against pathogens, by acting on NADP/H metabolism.
Objective
The European Commission aims at promoting agricultural innovation while preserving biodiversity and without increasing arable land surface. Understanding how plants respond to stress is therefore vital to design new, improved agricultural solutions that meet these requirements.
General and conserved plant stress responses to pathogens rely on systemic propagation of Calcium (Ca2+) signalling and reactive oxygen species (ROS) from the site of attack to distant organs. An unexpected, essential link between primary metabolism (i.e. NADP/H production), long-distance Ca2+ signals and ROS propagation was recently brought to light, thus opening a new line of fundamental research (i.e. the metabolic regulation of plant stress signalling) and suggesting that modulation of NADP metabolism can boost plant defences.
DEMEtRA (DEcoding Metabolic Effectors in plant sTress Response and Acclimation) aims at obtaining a deep characterization of this metabolic regulation of plant signalling in response to bacterial pathogens by combining biochemical and cutting-edge imaging techniques. This project will produce a thorough characterization of the NADP/H production mechanism and of the perturbations of long-distance signalling caused by a shortage of NADP/H. Finally, it will allow engineering new solutions to improve plant stress responses against pathogens, by acting on NADP/H metabolism. Thus, DEMEtRA will quickly advance fundamental research on plant stress signalling and guide biotechnological applications to improve conserved, natural defence mechanisms in crop plants.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences inorganic chemistry alkaline earth metals
- natural sciences biological sciences ecology ecosystems
- agricultural sciences agriculture, forestry, and fisheries agriculture
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
20122 Milano
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.