Project description DEENESFRITPL Industry-compatible catalysts for the synthesis of amines A variety of industries, including the pharmaceuticals, polymers and agrochemicals industries, use chemicals called amines. Traditional methods for making amines are inefficient in resources and energy; as a result, they are expensive and produce wasteful by-products. Alternative pathways to synthesise amines involve catalysis that is 100 % atom-efficient, facilitated by earth-abundant titanium catalysts. This catalysis offers significant environmental advantages over traditional methods, but it is not cost-effective for the industrial scale because separating the catalysts from the products is expensive. In this context, the EU-funded SiTi-CAT project will develop titanium catalysts for amine synthesis that can be easily and cheaply separated from the products. This will ensure that their widespread use is more attractive to industries and that amines can be produced in a more efficient way. Show the project objective Hide the project objective Objective Amines are commercially valuable compounds used in a wide range of products including pharmaceuticals, agrochemicals and polymers (global market USD 16.6 billion), but their industrial synthesis is inefficient and expensive. Alternatively, nitrogen functional groups can be synthesised by green, 100% atom efficient reactions (hydroamination and hydroaminoalkylation) that are catalysed by earth-abundant homogeneous Ti complexes. These reactions are not yet industrially viable due to high costs of catalyst recovery and product purification. We need to develop catalysts for these processes that exhibit the high activity and selectivity of homogeneous Ti catalysts but are industrially viable.This project will develop new heterogeneous catalysts for introducing nitrogen functional groups by immobilising Ti complexes based on homogeneous catalysts for hydroamination and hydroaminoalkylation onto silica surfaces. It will blend the disciplines of chemical synthesis, homogeneous catalysis, and surface organometallic chemistry by using the expertise of researchers and specialist facilities in Canada and France. I will: synthesise novel catalysts featuring well-defined Ti metal centres supported by ligands immobilised on silica surfaces, optimise their activity for hydroamination and hydroaminoalkylation on industrially important substrates, and investigate the mechanism of the reactions to optimise and enhance industrial applicability.This project will transform green processes to manufacture nitrogen-containing chemicals from academic research into industrial routes. Knowledge and key skills in chemical synthesis, catalyst development and surface organometallic chemistry will be shared between European and Canadian researchers, resulting in a synergic partnership impacting academic and industrial fields. I will apply my previous experience and learn new technical and transferable skills, which will advance me to my goal of becoming an independent academic researcher. Fields of science natural scienceschemical sciencesinorganic chemistryorganometallic chemistrynatural scienceschemical sciencesinorganic chemistrytransition metalsnatural scienceschemical sciencespolymer sciencesnatural scienceschemical sciencescatalysisnatural scienceschemical sciencesorganic chemistryamines Programme(s) HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme Topic(s) HORIZON-MSCA-2021-PF-01-01 - MSCA Postdoctoral Fellowships 2021 Call for proposal HORIZON-MSCA-2021-PF-01 See other projects for this call Funding Scheme HORIZON-AG-UN - HORIZON Unit Grant Coordinator CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Net EU contribution € 291 785,28 Address Rue michel ange 3 75794 Paris France See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITY OF BRITISH COLUMBIA Canada Net EU contribution € 0,00 Address Agronomy road 102-6190 V6T1Z1 Vancouver See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
