Objective
Photoredox catalysis has become a quintessential part of organic synthesis and gained wide interest in the chemical industry as a mild and robust synthetic methodology. Acridinium salts are a prominent substitute for transition metal-based photocatalysts (PCs) due to the modularity of the core, which makes them and structurally related dyes an optimal platform for structure-property tuning. However, a limited understanding of how structure influences reactivity prevents rational design, while the synthetically realizable chemical space is far too vast to explore using even high-throughput experimental methods.
The objective of the proposed action is to study computationally the elementary mechanistic steps integral to photoredox catalysis to establish how they are each influenced by PC structure. We will develop an automated workflow for high-throughput computational molecular PC construction and analysis, in which known molecular fragments are coupled together by chemically precedented steps. Finally, Bayesian optimization will be used to guide the machine learning model building. This is distinct from conventional approaches in the field as we aim to increase the quality of our model with mechanistic understanding from quantum chemical calculation.
My expertise in the fields of synthetic, physical, and computational organic chemistry, provide me the necessary skillset and ability to learn new concepts and successfully execute this project. The gained knowledge and results from the project will be an asset and help to build sustainable processes in the chemical industry in EU. The work will be implemented in the research groups of Prof. Robert Paton and Prof. Jeremy Harvey, with a secondment period in the group of Prof. Abigail Doyle. The investigators’ combined expertise ranges from computational and empirical reaction mechanism study to data sciences, and hence enables the project to incorporate complex mechanistic information to rational PC design.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology materials engineering synthetic dyes
- natural sciences chemical sciences physical chemistry quantum chemistry
- natural sciences chemical sciences catalysis
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-GF - HORIZON TMA MSCA Postdoctoral Fellowships - Global Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3000 LEUVEN
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.