Project description
Application of Lactobacillus plantarum extracellular vesicles in allergy treatment
Funded by the Marie Skłodowska-Curie Actions programme, the LactoVES project aims to investigate the immunomodulatory properties of Lactobacillus plantarum extracellular vesicles and their potential application in the treatment and prevention of airway allergies. The project will characterise the physicochemical properties of the vesicles, using in vitro testing in respiratory epithelial cell lines, followed by in vivo tests in mouse models of airway allergy. The project will combine the comprehensive physicochemical characterisation of extracellular vesicles with advanced immunological research.
Objective
The aim of the project is to conduct basic scientific research on the immunomodulatory properties of Lactobacillus plantarum (L. plantarum) extracellular vesicles in terms of their applicability in the treatment/prevention of airway allergies. The project assumes a comprehensive characterization of vesicles, starting from the description of their physicochemical properties, through in vitro tests using respiratory epithelial cell lines, to in vivo tests on mouse models of airway allergy. The project combines two areas, both the physicochemical characteristics of nanoparticles such as extracellular vesicles and advanced immunological research.
Fields of science
Keywords
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European FellowshipsCoordinator
1090 Wien
Austria