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Immunomodulatory properties of L. plantarum extracellular vesicles in airway allergy

Project description

Application of Lactobacillus plantarum extracellular vesicles in allergy treatment

Funded by the Marie Skłodowska-Curie Actions programme, the LactoVES project aims to investigate the immunomodulatory properties of Lactobacillus plantarum extracellular vesicles and their potential application in the treatment and prevention of airway allergies. The project will characterise the physicochemical properties of the vesicles, using in vitro testing in respiratory epithelial cell lines, followed by in vivo tests in mouse models of airway allergy. The project will combine the comprehensive physicochemical characterisation of extracellular vesicles with advanced immunological research.

Objective

The aim of the project is to conduct basic scientific research on the immunomodulatory properties of Lactobacillus plantarum (L. plantarum) extracellular vesicles in terms of their applicability in the treatment/prevention of airway allergies. The project assumes a comprehensive characterization of vesicles, starting from the description of their physicochemical properties, through in vitro tests using respiratory epithelial cell lines, to in vivo tests on mouse models of airway allergy. The project combines two areas, both the physicochemical characteristics of nanoparticles such as extracellular vesicles and advanced immunological research.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

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(opens in new window) HORIZON-MSCA-2021-PF-01

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Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 199 440,96
Address
SPITALGASSE 23
1090 Wien
Austria

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Region
Ostösterreich Wien Wien
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Partners (1)

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