Project description
Understanding solid food swallowing by developing more realistic in vitro models
As we age, most body functions undergo changes. Depending on an individual’s overall health profile, some of the physiological processes may even become impaired. Dysphagia – difficulty swallowing – is a serious concern for older adults and other vulnerable groups as it can lead to malnutrition or even choking. Funded by the Marie Skłodowska-Curie Actions programme, the SENSINGTech project will study the interaction between food characteristics and saliva production upon food intake to evaluate mastication and swallowing in healthy and dysphagic individuals. The project’s work will lead to the first-of-its-kind in vitro approach that mimics the human feeding process, unravelling the mechanisms that may disrupt it.
Objective
The main goal of oral processing is preparing food for swallowing and digestion, where mastication determines the effective surface area of food particles and food bolus properties. Ageing induces changes in oral physiology leading to substantial alterations in bolus properties, bioaccessibility, and bioavailability of nutrients. The impact of age-related alterations on swallowing and digestion can be intensified by health conditions that may cause dysphagia. SENSINGTech is an interdisciplinary research project that, integrating a full sensor-based technological platform, aims to investigate the evolution of food properties in mouth, and the dynamics of food oral processing and saliva addition on bolus formation, to quantify its impact on both swallowing and the delivery of nutrients. This work aims to provide clear-cut boundaries of food characteristics that ensure a safe swallow. The key limitation of working with vulnerable people to accurately measure mastication, swallowing and digestion will be overcome by developing a quantitative in vitro approach that mimics the human feeding process, monitoring the “Stage II of transport” for solid food intake – not captured by any in vitro system yet. This project will enable the fellow to acquire a strong competence in food oral processing, swallowing, and digestion, learning new methodologies and applications to meet the challenges linked to population ageing and the management of dysphagia. This research will address the Horizon Europe (HE) efforts devoted to “Health”, where the unique combination of expertise will lead the candidate towards an independent scientist career of high quality and strong international visibility. SENSINGTech will therefore be a milestone for the future research career of the applicant, positioning both the fellow and the host in leading positions in food oral processing and the dysphagia research field.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75007 PARIS CEDEX 07
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.