Prevention, mitigation, management of infectious diseases on cruise ships and passenger ferries

Livrables

Terms of reference - International expert panel

Terms of reference International expert panel M6 The deliverable will provide the terms of reference of an international scientific group for exchange and harmonisation of best practices at an international levelD62 Terms of reference International expert panel refers to T31 Initialisation of research and innovation activities kick off meeting T63 Establishment of the framework for an international scientific committee for infectious diseases related to passenger ships

Foundation report (revised version)

Foundation report (M12, revised version).D3.5 Foundation report revised refers to: T1.3: Integration of General Data Protection Regulation (GDPR), legal assessments of project outputs and establishment of independent research ethics committeeT3.1: Initialisation of research and innovation activities kick off meeting T3.2: Preparation of the foundation report

Report from intervention studies & pilot-runs (first version)

Report from intervention studies & pilot-runs. It will describe the evidence produced through the experimental studies, intervention studies, pilot-runs and technological demonstrations (M6 first version).D3.2 Report from intervention studies & pilot-runs (first version) refers to: T1.3: Integration of General Data Protection Regulation (GDPR), legal assessments of project outputs and establishment of independent research ethics committeeT3.1: Initialisation of research and innovation activities kick off meeting T3.3: Analysis of infection chain, health risk assessment and setting of risk-based measures prioritiesT3.5: Mathematical modelling of infectious disease spread on-board large passenger shipsT3.6: Pilot-run, validation and technological demonstration

Inventory of diagnostic laboratory methods

Inventory of diagnostic laboratory methods for infectious agents (clinical, environmental samples) (M20). The inventory will provide the methods and technologies that will allow the passenger ships to deal with large number and wide range of clinical and environmental samples.D5.3 Inventory of diagnostic laboratory methods refers to: T3.1: Initialisation of research and innovation activities kick off meeting T3.8: Integration of project outputs in the existing operational frameworks T5.3: Inventory of diagnostic laboratory methods for infectious agents (clinical/environmental samples).

Foundation report for COVID-19 related preliminary results

Foundation report M6for COVID19 related preliminary results The report will include the results from studies and reviews conductedD31 Foundation report for COVID19 related preliminary results refers to T13 Integration of General Data Protection Regulation GDPR legal assessments of project outputs and establishment of independent research ethics committeeT31 Initialisation of research and innovation activities kick off meeting T32 Preparation of the foundation report

Report from intervention studies & pilot-runs (for COVID-19 related preliminary results)

Report from intervention studies & pilot-runs. It will describe the evidence produced through the experimental studies, intervention studies, pilot-runs and technological demonstrations (M18 for COVID-19 related preliminary results).D3.6 Report from intervention studies & pilot-runs (for COVID-19 related preliminary results) refers to:T1.3: Integration of General Data Protection Regulation (GDPR), legal assessments of project outputs and establishment of independent research ethics committeeT3.1: Initialisation of research and innovation activities kick off meeting T3.3: Analysis of infection chain, health risk assessment and setting of risk-based measures prioritiesT3.5: Mathematical modelling of infectious disease spread on-board large passenger shipsT3.6: Pilot-run, validation and technological demonstration

Procedures for syndromic surveillance

Procedures for syndromic surveillance. It will describe the infectious disease surveillance definitions, procedures for large passenger ships (M18).D4.1 Procedures for syndromic surveillance refers to: T3.1: Initialisation of research and innovation activities kick off meeting T3.3: Analysis of infection chain, health risk assessment and setting of risk-based measures priorities T4.1: Design, development and testing of syndromic surveillance system of infectious disease for large passenger shipsT4.2: User and system requirements and modelling for machine learning and AI in E-SS and IIST4.5: Procedures for facilitated access to health care on-board (ship doctor, medical staff) for crew and passengers to enhance surveillance for infectious diseases T5.1: Defining procedures for incorporating environmental samples laboratory results, ship monitoring parameters and audit/monitoring inspections in the integrated e-surveillance system for health threats (E-SS)

Report on computational modelling of droplet and aerosol dispersion (model validation report)

Report on computational modelling of droplet and aerosol dispersion in different ship environments (M20 - model validation report).D3.8 Report on computational modelling of droplet & aerosol dispersion (model validation report) refers to:T3.1: Initialisation of research and innovation activities kick off meeting T3.4: Computational modelling of droplet and aerosol dispersion in different ship environments Recommendations for air quality and ventilation

Midterm recruitment report

Midterm recruitment report for ethics requirements related to the clinical study under D7.1 (M18).D7.5 Midterm recruitment report refers to: T1.3: Integration of General Data Protection Regulation (GDPR), legal assessments of project outputs and establishment of independent research ethics committeeT3.1: Initialisation of research and innovation activities kick off meeting T3.6: Pilot-run, validation and technological demonstration T3.7: Development of evidence-informed guidelines for infectious disease PMM measures T7.1: Technology induced behavioural change in hand hygiene management

Evidence-based guidelines (COVID-19 interim guidelines)

Evidence-based guidelines for: specificities/needs of medical operations in expedition vessels; passenger and crew vaccination in large passenger ships; COVID-19 prevention, mitigation, control in routine operations and ventilation on passenger ships (M6-COVID-19 interim guidelines).D3.4 (Evidence-based guidelines (COVID-19 interim guidelines) refers to: T3.1: Initialisation of research and innovation activities kick off meeting T3.6: Pilot-run, validation and technological demonstrationT3.7: Development of evidence-informed guidelines for infectious disease PMM measuresT3.8: Integration of project outputs in the existing operational frameworks

Study Initiation Package

Study initiation package for ethics requirements related to the clinical study under D71 M3D74 Study initiation package refers to T13 Integration of General Data Protection Regulation GDPR legal assessments of project outputs and establishment of independent research ethics committeeT31 Initialisation of research and innovation activities kick off meeting T36 Pilotrun validation and technological demonstration T37 Development of evidenceinformed guidelines for infectious disease PMM measures T71 Technology induced behavioural change in hand hygiene management

Report on computational modelling of droplet and aerosol dispersion (validation data report)

Report on computational modelling of droplet and aerosol dispersion in different ship environments (M12-validation data report. Report will detail experimental and modelling studies on droplet and aerosol dispersion and mitigation efficacy.D3.3 Report on computational modelling of droplet & aerosol dispersion (validation data report) refers to: T3.1: Initialisation of research and innovation activities kick off meeting T3.4: Computational modelling of droplet and aerosol dispersion in different ship environments Recommendations for air quality and ventilation

Blended Learning training toolkit enriched with hands-on training (HOT) - first version for COVID-19 module

Blended Learning training toolkit enriched with hands-on training (HOT): training and education for passengers, for crew, for non-health professionals involved in ship and port operations (M6 1st version for COVID-19 module). The deliverable will contain the material for the training programme.D7.2 Blended Learning training toolkit enriched with hands-on training (HOT) first version for COVID-19 module refers to: T3.1: Initialisation of research and innovation activities kick off meeting T3.6: Pilot-run, validation and technological demonstration T3.7: Development of evidence-informed guidelines for infectious disease PMM measures T7.2: Designing and developing a training curriculum incorporating Augmented Reality technology and GamificationT7.3: Technical content of training materials.T7.4: Blended Learning training toolkit enriched with hands-on training

Publications

Monitoring of indoor air quality at a large sailing cruise ship to assess ventilation performance and disease transmission risk

Auteurs: Ho Yin Wickson Cheung, Prashant Kumar, Sarkawt Hama, Ana Paula Mendes Emygdio, Yingyue Wei, Lemonia Anagnostopoulos, John Ewer, Valerio Ferracci, Edwin R. Galea, Angus Grandison, Christos Hadjichristodoulou, Fuchen Jia, Pierfrancesco Lepore, Lidia Morawska, Varvara A. Mouchtouri, Niko Siilin, Zhaozhi Wang
Publié dans: Science of The Total Environment, Numéro 962, 2025, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2024.178286

Scoping review of infectious disease prevention, mitigation and management in passenger ships and at ports: mapping the literature to develop comprehensive and effective public health measures

Auteurs: Lemonia Anagnostopoulos, Sotirios Vasileiadis, Leonidas Kourentis, Zacharoula Bogogiannidou, Ioanna Voulgaridi, Gordon Nichols, Fani Kalala, Matthaios Speletas, Christos Hadjichristodoulou, Varvara A. Mouchtouri, null null, Angelos Amditis, Spyridon Athanasiadis, Szava J. Bansaghi, Despoina A. Bygvraa, Stefanos Chatzimichelakis, Reuben D’Souza, Dimitra Dionysiou, Maria Guerrero-Vadillo, Giorgio Guzzetta, Volker Harth, Jan Heidrich, Jörn Klein, Jürgen F. Kolb, Prashant Kumar, Pierfrancesco Lepore, Sergiu Lupu, Valentina Marziano, Johannes Neumann, Symeon Nikolaou, Filip Nistor, Eleftherios Ouzounoglou, Vassilis Papataxiarhis, Marina Peñuelas, Patrizio Pezzotti, Catalin Popa, Raphael Rataj, Smaragda Reppa, Flavia Riccardo, Hannu Salmela, Niko Siilin, Konstantinos Theofilis, Constantinos Tsibanis, Carmen Varela, Nikolaos P. Ventikos, Georgios Vosinakis, Goran Vukelić, Christine Zädow, Vassilios Zagkas
Publié dans: Tropical Medicine and Health, Numéro 53, 2025, ISSN 1349-4147
Éditeur: Springer Science and Business Media LLC
DOI: 10.1186/s41182-025-00681-0

Airborne pathogen monitoring and dispersion modelling on passenger ships: A review

Auteurs: Prashant Kumar, Sarkawt Hama, Ho Yin Wickson Cheung, Christos Hadjichristodoulou, Varvara A. Mouchtouri, Lemonia Anagnostopoulos, Leonidas Kourentis, Zhaozhi Wang, Edwin R. Galea, John Ewer, Angus Grandison, Fuchen Jia, Niko Siilin
Publié dans: Science of The Total Environment, Numéro 980, 2025, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/J.SCITOTENV.2025.179571

Interventional Study of Nonpharmaceutical Measures to Prevent COVID-19 Aboard Cruise Ships

Auteurs: Varvara A Mouchtouri, Leonidas Kourentis, Lemonia Anagnostopoulos, Michalis Koureas, Maria Kyritsi, Katerina Maria Kontouli, Fani Kalala, Mattheos Speletas, Christos Hadjichristodoulou
Publié dans: Emerging Infectious Diseases, 2024, ISSN 1080-6059
Éditeur: CDC
DOI: 10.3201/eid3005.231364

EVALUATION OF THE ANTIMICROBIAL EFFECT OF A FAR-UV RADIATION LAMP IN A REAL-LIFE ENVIRONMENT

Auteurs: Szava Bansaghi, Jörn Klein
Publié dans: Infection Prevention in Practice, Numéro 100390, 2024, ISSN 2590-0889
Éditeur: Infection Prevention in Practice
DOI: 10.1016/j.infpip.2024.100390

Behavioural aspects among Cruise Ships Passengers affecting the Spread of Infectious Diseases including COVID-19: A Systematic Review

Auteurs: Sheila Siame, Despoina Andrioti Bygvraa*, Delér Shakely, Lynn M Hulse, Varvara Mouchtouri and Christos Hadjichristodoulou for the HEALTHY SAILING project consortium
Publié dans: Oceanography and Fisheries, Numéro 17(1), 2023, ISSN 2476-0536
Éditeur: Juniper
DOI: 10.19080/OFOAJ.2023.17.555953

Factors influencing the occurrence of infectious diseases among crew members on board cruise ships: a systematic review

Auteurs: Sheila Siame, Despoina Andrioti Bygvraa, Lynn M. Hulse Hulse, Varvara Mouchtouri, Christos Hadjichristodoulou
Publié dans: International Maritime Health, 2025, ISSN 1641-9251
Éditeur: International Maritime Health
DOI: 10.5603/imh.98558

Forecasting norovirus cases on cruise ships to support outbreak management on board

Auteurs: Andrea Bizzotto, Alfredo De Bellis, Valentina Marziano, Varvara A. Mouchtouri, Leonidas Kourentis, Lemonia Anagnostopoulos, Christos Hadjichristodoulou, Stefano Merler, Giorgio Guzzetta
Publié dans: Travel Medicine and Infectious Disease, Numéro 65, 2025, ISSN 1477-8939
Éditeur: Elsevier BV
DOI: 10.1016/J.TMAID.2025.102850

Systematic literature review and meta-analysis on preventing and controlling norovirus outbreaks on cruise ships, 1990 to 2020: calling for behaviour change strategies of travellers

Auteurs: Varvara A Mouchtouri, Evangelia Simou, Soteris Soteriades, Xanthoula Rousou, Katerina Maria Kontouli , Dimitra Kafetsouli , Leonidas Kourentis, Lemonia Anagnostopoulos, Christos Hadjichristodoulou
Publié dans: Eurosurveillance, Numéro 29 (10), 2024, ISSN 1560-7917
Éditeur: ECDC
DOI: 10.2807/1560-7917.ES.2024.29.10.2300345

Healthy Sailing: Prevention, Mitigation and Management of Infectious Disease on Cruise Ships and Passenger Ferries

Auteurs: Varvara A. Mouchtouri, Edwin Galea, Prashant Kumar, Niko Siilin, Juergen F. Kolb, Nikolaos P. Ventikos, Vassilis Papataxiarhis, Georgios Vosinakis, Jörn Klein, Christos Hadjichristodoulou, for the HEALTHY SAILING project consortium
Publié dans: 2024
Éditeur: "##"

Introducing Maritime Educational Standard for Mitigation of Infectious Diseases Spread on Large Passenger Ships

Auteurs: Goran Vukelić, Goran Vizentin, Jörn Klein
Publié dans: Proceedings of the 23rd International Association of Maritime Universities Conference, 2023, ISSN 2706-6762
Éditeur: Satakunta University of Applied Sciences, Finland

Developing a Framework for Health Risk Assessment, by Integrating Infection and Spreading Aspects into RBD

Auteurs: Nikolaos P. Ventikos, Panagiotis Sotiralis, Manolis Annetis
Publié dans: Medical Science Forum 2022, 2022, ISSN 2673-9992
Éditeur: MDPI
DOI: 10.3390/msf2022013002

Effectiveness of antimicrobial sprays applied on frequently touched surfaces

Auteurs: Bansaghi S., Klein J.
Publié dans: Antimicrobial Resistance & Infection Control, 2023, ISSN 2047-2994
Éditeur: Antimicrobial Resistance & Infection Control
DOI: 10.1186/s13756-023-01276-2

Health Risk Assessment in Maritime Operations and Ship Design: a Framework for addressing Health-related Risks in the context of Maritime Safety Assessment

Auteurs: Ventikos, Nikolaos P.; Sotiralis, Panagiotis; Annetis, Manolis
Publié dans: 2023 7th International Conference on Transportation Information and Safety (ICTIS), 2023, ISSN 2832-899X
Éditeur: IEEE
DOI: 10.1109/ictis60134.2023.10243723

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