Objective Understanding and controlling complex systems at different scales is a major challenge in biology and medicine. Quantum sensing technologies hold much promise for disruptive approaches to imaging and spectroscopy of biological matter. MUQUABIS aims at developing synergetic tools of quantum bio-sensing and bio-imaging. Such sensors will offer biology a distinctive host of powerful features – non-invasiveness, sensitivity, spatial and temporal resolutions, likely to conquer new frontiers in imaging and spectroscopy, out-of-reach of their classical counterparts. A focus is a global structural and functional understanding of cardiac cell layers from molecules to cells to tissues. ¬Their study in healthy and diseased conditions will shed light on cardiac arrhythmias, largely responsible for morbidity and sudden cardiac death. Advancing beyond modern tools of photonics and quantum measurements, new concepts for quantum frequency combs and infrared lasers will be explored. Low-light-level spectro-imaging will detect cell-membrane proteins and gaseous metabolites nearby cell tissues, below the quantum noise limit. Concurrently, a quantum magneto-microscope based on diamond nitrogen-vacancy centers will be combined to optical imaging for electrophysiology. Such a hybrid sensor will simultaneously and locally reveal the magnetic and electric fields in cardiac-cell activity. MUQUABIS proposes a unique synergic effort, gathering complementary expertise, technologies and infrastructures. Leading research institutions in quantum sensing, quantum optics and biophysics, together with four high-tech companies will rapidly move the project from fundamental quantum sensing components and protocols to technology validation on biological samples to a roadmap for industrial exploitation. MUQUABIS will pave the way to ground-breaking quantum-based tools and protocols for medical diagnostics and treatments, a strategic objective for the European Quantum Technology flagship. Fields of science medical and health sciencesclinical medicinecardiologycardiovascular diseasescardiac arrhythmiaengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural sciencesphysical sciencesquantum physicsquantum opticsnatural sciencesbiological sciencesbiophysicsnatural sciencesphysical sciencesopticsspectroscopy Keywords Quantum sensing technologies Medical diagnostic and imaging Quantum magnetometry Quantum optics NV centers in diamond Quantum frequency combs Quantum cascade lasers Programme(s) HORIZON.2.4 - Digital, Industry and Space Main Programme HORIZON.2.4.2 - Key Digital Technologies Topic(s) HORIZON-CL4-2021-DIGITAL-EMERGING-01-21 - Next generation quantum sensing technologies (RIA) Call for proposal HORIZON-CL4-2021-DIGITAL-EMERGING-01 See other projects for this call Funding Scheme RIA - Research and Innovation action Coordinator CONSIGLIO NAZIONALE DELLE RICERCHE Net EU contribution € 1 899 290,00 Address Piazzale aldo moro 7 00185 Roma Italy See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (8) Sort alphabetically Sort by Net EU contribution Expand all Collapse all MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Germany Net EU contribution € 850 367,50 Address Hofgartenstrasse 8 80539 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 JOHANNES GUTENBERG-UNIVERSITAT MAINZ Germany Net EU contribution € 800 105,00 Address Saarstrasse 21 55122 Mainz See on map Region Rheinland-Pfalz Rheinhessen-Pfalz Mainz, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE HEBREW UNIVERSITY OF JERUSALEM Israel Net EU contribution € 800 000,00 Address Edmond j safra campus givat ram 91904 Jerusalem See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITA CAMPUS BIO MEDICO DI ROMA Italy Net EU contribution € 519 706,00 Address Via alvaro del portillo 21 00128 Roma See on map Region Centro (IT) Lazio Roma Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,25 FAKULTNI NEMOCNICE U SV ANNY V BRNE Czechia Net EU contribution € 498 860,00 Address Pekarska 53 602 00 Brno See on map Region Česko Jihovýchod Jihomoravský kraj Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LEONARDO - SOCIETA PER AZIONI Italy Net EU contribution € 496 250,00 Address Piazza monte grappa 4 00195 Roma See on map Region Centro (IT) Lazio Roma Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 QLIBRI GMBH Germany Net EU contribution € 399 962,50 Address Maistrasse 67 80337 Munchen See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 PPQSENSE SRL Italy Net EU contribution € 400 000,00 Address Viale ludovico ariosto 492/b 50019 Sesto fiorentino See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Centro (IT) Toscana Firenze Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all ELEMENT SIX (UK) LIMITED Participation ended United Kingdom Net EU contribution € 0,00 Address Global innovation centre fermi avenue OX11 0QR Harwell oxfordshire didcot See on map Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
