Remote whole-brain functional microscopy of the vascular system: a paradigm shift for the monitoring and treatment of small vessel diseases

Project Information

MICROVASC

Grant agreement ID: 101070917

DOI

10.3030/101070917

EC signature date 11 July 2022

Start date 1 October 2022

End date 30 September 2027

Funded under

• The European Innovation Council (EIC)

Total cost

€ 3 946 172,50

EU contribution

€ 3 946 172,50

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (2)

RP2 update of the DMP

First update of the Data Management Plan (DMP).

DMP

Initial version of the Data Management Plan DMP to be updated at the end of each reporting period 23 and 4

Documents, reports (1)

Preclinical protocol

D4.1 (M18): Preclinical protocol

Websites, patent fillings, videos etc. (1)

MICROVASC website and project logo

Website and project logo is scheduled at month 2 M2 and continuously updated thereafter Website address should be related to the title of the project and have the address in the eu domain

Publications

Peer reviewed articles (8)

Spontaneous spreading depolarizations originate subcortically in a novel mouse model of familial hemiplegic migraine type 2

Author(s): Nico A. Jansen, Chelsey Linnenbank, Maarten Schenke, Rob A. Voskuyl, Maria S. Jorge, Georgii Krivoshein, Cor Breukel, Margot M. Linssen, Jill W.C. Claassens, Conny Brouwers, Sandra H. van Heiningen, Anders Heuck, Karin Lykke-Hartmann, Else A. Tolner, Arn M.J.M. van den Maagdenberg
Published in: Neurobiology of Disease, Issue 202, 2024, ISSN 0969-9961
Publisher: Elsevier BV
DOI: 10.1016/J.NBD.2024.106714

Physio-fUS: a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging

Author(s): Nicolas Zucker, Samuel Le Meur-Diebolt, Felipe Cybis Pereira, Jérôme Baranger, Isabella Hurvitz, Charlie Demené, Bruno-Félix Osmanski, Nathalie Ialy-Radio, Valérie Biran, Olivier Baud, Sophie Pezet, Thomas Deffieux, Mickael Tanter
Published in: eBioMedicine, Issue 112, 2025, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/J.EBIOM.2025.105581

Non-invasive characterization of pericyte dysfunction in mouse brain using functional ultrasound localization microscopy

Author(s): Jérémy H. Thalgott, Nicolas Zucker, Thomas Deffieux, Marit S. Koopman, Alexandre Dizeux, Cristina M. Avramut, Roman I. Koning, Hans-Jurgen Mager, Ton J. Rabelink, Mickaël Tanter, Franck Lebrin
Published in: Nature Biomedical Engineering, Issue 10, 2026, ISSN 2157-846X
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41551-025-01465-X

Imaging and Quantification of the Hepatic Vasculature of Mice Using Ultrafast Doppler Ultrasound

Author(s): Katerina Stripling, Finn Timmermans, Sofiane Décombas-Deschamps, Jérémy H. Thalgott, David Lemonnier, Margreet R. de Vries, Ton J. Rabelink, Mickael Tanter, Thomas Deffieux, Franck Lebrin
Published in: Journal of Visualized Experiments, 2024, ISSN 1940-087X
Publisher: MyJove Corporation
DOI: 10.3791/66789

Spontaneous and optogenetically induced cortical spreading depolarization in familial hemiplegic migraine type 1 mutant mice

Author(s): Inge C.M. Loonen, Rob A. Voskuyl, Maarten Schenke, Sandra H. van Heiningen, Arn M.J.M. van den Maagdenberg, Else A. Tolner
Published in: Neurobiology of Disease, Issue 192, 2025, ISSN 0969-9961
Publisher: Elsevier BV
DOI: 10.1016/J.NBD.2024.106405

Physio-fUS: a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging

Author(s): Nicolas Zucker, Samuel Le Meur-Diebolt, Felipe Cybis Pereira, Jérôme Baranger, Isabella Hurvitz, Charlie Demené, Bruno-Félix Osmanski, Nathalie Ialy-Radio, Valérie Biran, Olivier Baud, Sophie Pezet, Thomas Deffieux, Mickael Tanter
Published in: eBioMedicine, Issue 112, 2025, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/J.EBIOM.2025.105581

In vivo microvascular flow quantification in the mouse brain using row–column ultrasound localization microscopy and directed graph analysis

Author(s): Adrien Bertolo, Jeremy Ferrier, Oscar Demeulenaere, Alexandre Dizeux, Tanguy Delaporte, Bruno Osmanski, Mickael Tanter, Mathieu Pernot, Thomas Deffieux
Published in: Journal of Cerebral Blood Flow & Metabolism, 2026, ISSN 0271-678X
Publisher: SAGE Publications
DOI: 10.1177/0271678X261438569

In vivo microvascular flow quantification in the mouse brain using row–column ultrasound localization microscopy and directed graph analysis

Author(s): Adrien Bertolo, Jeremy Ferrier, Oscar Demeulenaere, Alexandre Dizeux, Tanguy Delaporte, Bruno Osmanski, Mickael Tanter, Mathieu Pernot, Thomas Deffieux
Published in: Journal of Cerebral Blood Flow & Metabolism, Issue 46, 2026, ISSN 0271-678X
Publisher: SAGE Publications
DOI: 10.1177/0271678X261438569