Periodic Reporting for period 1 - HYPERSTIM (High-dimensional electrical stimulation for visual prosthesis)
Período documentado: 2022-11-01 hasta 2023-10-31
- succesful fabricaton of thin, flexible electrode arrays for recording and microstimulation
- implantation of several hundred electrodes in visual cortex of nonhuman primates
- first calcium imaging experiments using thin flexible electrode arrays in mice
- recordings of neural activity in visual cortex of nonhuman primates for several months up to 2.5 years
- demonstration of the effect of epicranial transcranial direct current stimulation (EDCS) on neural activity
- a computational model of the mouse visual cortex allowing simulations of the effect of a high number of stimulation patterns
- reliable decoding of orientation based on the recordings in visual cortex of NHPs
- induction of phosphenes by microstimulation in visual cortex
- charting fMRI activations caused by microstimulation in visual cortex
The possibility to measure functional activations caused by microstimulation is another significant advantage over other electrode arrays.