Living Therapeutic and Regenerative Materials with Specialised Advanced Layers

Livrables

Contribution to the regulatory debate in RP2

Report on the activities, outcomes and planned follow up to assess and address the ELMs portfolio needs. This includes contribution to the regulatory debate by engaging early on and continuously with regulatory bodies. Any confidential information related to these activities will be included in the technical report.

Website and project logo

This report will include the project logo and it will describe the website functionalities. The report will also explain how the website is used for in- and outward communication.Social media links will also be provided.

Contribution to the regulatory debate in RP1

Report on the activities, outcomes and planned follow up to assess and address the ELMs portfolio needs. This includes contribution to the regulatory debate by engaging early on and continuously with regulatory bodies. Any confidential information related to these activities will be included in the technical report.

Portfolio’s Dissemination and communication activities RP1

The report includes a description of the activities, the outcomes and any planned follow up.

ELSA activities in RP1

Report on the activities, outcomes and planned follow up to address ethical, legal and social aspects (ELSA). These activities include engagement with strategic partners (including the public), and dissemination of best practices and guidelines when applicable with the ELMs field. Any confidential information related to these activities will be included in the technical report.

Portfolio’s Dissemination and communication activities RP2

The report includes a description of the activities, the outcomes and any planned follow up.

ELSA activities in RP2

Report on the activities, outcomes and planned follow up to address ethical, legal and social aspects (ELSA). These activities include engagement with strategic partners (including the public), and dissemination of best practices and guidelines when applicable with the ELMs field. Any confidential information related to these activities will be included in the technical report.

Publications

The influence of substrate and ethanol treatment on properties and quantitative analysis of retention of recombinant spider silk coatings

Auteurs: Maaria Malkamäki, Kristoffer Meinander, Markus B. Linder
Publié dans: International Journal of Biological Macromolecules, Numéro 340, 2026, ISSN 0141-8130
Éditeur: Elsevier BV
DOI: 10.1016/J.IJBIOMAC.2026.150105

Modulating Microbial Materials - Engineering Bacterial Cellulose with Synthetic Biology

Auteurs: Koray Malcı, Ivy S. Li, Natasha Kisseroudis, Tom Ellis
Publié dans: ACS Synthetic Biology, Numéro 13, 2024, ISSN 2161-5063
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSSYNBIO.4C00615

Leveraging the versatile properties of bacterial spores in materials

Auteurs: Likhitha Reddy Kummetha, Jeong-Joo Oh, Franka H. van der Linden, Marie-Eve Aubin-Tam
Publié dans: Trends in Biotechnology, 2024, ISSN 0167-7799
Éditeur: Elsevier BV
DOI: 10.1016/J.TIBTECH.2024.09.018

On-body biodesign: exploring the human body’s role in designing with living organisms

Auteurs: Fanzhe Zeng, Stefano Parisi, Joana Martins, Elvin Karana
Publié dans: Biotechnology Design, Numéro 4, 2026, ISSN 2977-9057
Éditeur: Cambridge University Press (CUP)
DOI: 10.1017/S2977905726100535

Slowpoke: An Automated Golden Gate Cloning Workflow for Opentrons OT-2 and Flex

Auteurs: Koray Malcı, Fankang Meng, Henri Galez, Alicia Franja Da Silva, Joaquin Caro-Astorga, Gregory Batt, Tom Ellis
Publié dans: ACS Synthetic Biology, Numéro 15, 2026, ISSN 2161-5063
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSSYNBIO.5C00629

Living Artefacts for Regenerative Ecologies

Auteurs: Karana E., McQuillan H., Rognoli V. & Giaccardi E.
Publié dans: Research Directions: Biotechnology Design, 2023, ISSN 2752-9460
Éditeur: Cambridge University Press
DOI: 10.1017/btd.2023.10

Seasonal Biodesign: Real-world Studies with Living Artefacts for Urban Biodiversity

Auteurs: Eduard Groutars, Joana Martins, Iohanna Nicenboim, Elvin Karana
Publié dans: Research Directions: Biotechnology Design, 2026, ISSN 2752-9452
Éditeur: Cambridge University Press (CUP)
DOI: 10.1017/S2977905726100651

YTK Display-and-Secrete: Screening for Optimal Protein Secretion Elements in <i>Saccharomyces cerevisiae</i>

Auteurs: Anastasiya Kishkevich, Klaudia Ciurkot, Tom Ellis
Publié dans: ACS Synthetic Biology, Numéro 14, 2025, ISSN 2161-5063
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSSYNBIO.5C00264

Societal implications of self-healing engineered living materials: insights from a co-design study

Auteurs: Verindi Vekemans, Stefano Parisi, Jun Wu, Elvin Karana
Publié dans: Biotechnology Design, Numéro 4, 2026, ISSN 2977-9057
Éditeur: Cambridge University Press (CUP)
DOI: 10.1017/S2977905726100559

Bacterially grown living materials with resistant and on-demand functionality

Auteurs: Jeong-Joo Oh, Franka H. van der Linden, Koray Malcı, Ramon A. van der Valk, Tom Ellis, Marie-Eve Aubin-Tam
Publié dans: Science Advances, Numéro 11, 2025, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADW8278

SubtiToolKit: a bioengineering kit for Bacillus subtilis and Gram-positive bacteria

Auteurs: Joaquin Caro-Astorga, Matt Rogan, Koray Malcı, Hia Ming, Erika Debenedictis, Paul James, Tom Ellis
Publié dans: Trends in Biotechnology, 2025, ISSN 0167-7799
Éditeur: Elsevier BV
DOI: 10.1016/J.TIBTECH.2025.02.004

International Journal of Design

Auteurs: Groutars EG., Kim R., Karana E.
Publié dans: International Journal of Design, 2024, ISSN 1991-3761
Éditeur: National Taiwan University of Science and Technology
DOI: 10.57698/v18i2.04

On the Habitabilities of Bacterial Cellulose for Living Artefacts

Auteurs: Eduard Georges Groutars, Joana Martins, Elvin Karana
Publié dans: Proceedings of the 2025 ACM Designing Interactive Systems Conference, 2025
Éditeur: ACM
DOI: 10.1145/3715336.3735432

The X_Heal Toolkit: Navigating Temporal and Dynamic Self-Healing Processes in Living Materials

Auteurs: Verindi Vekemans, Stefano Parisi, Fanzhe Zeng, Jun Wu, Elvin Karana
Publié dans: IASDR 2025: Design Next, 2026
Éditeur: Design Research Society
DOI: 10.21606/IASDR.2025.304

Surfacing Livingness in Microbial Displays: A Design Taxonomy for HCI

Auteurs: Kim R., Risseeuw C., Groutars E. G., & Karana E.
Publié dans: Proceedings of the 2023 CHI Conference on Human Factors in Computing Systems, 2023, ISBN 978-1-4503-9421-5
Éditeur: ACM, New York
DOI: 10.1145/3544548.3581417

Living Therapeutic Skin (LTS): Design Opportunities and Challenges of On-Skin Living Artefacts

Auteurs: Raphael Kim, Fanzhe Zeng, Tom Ellis, Elvin Karana
Publié dans: What's Around Design?, 2026
Éditeur: Springer Nature Switzerland
DOI: 10.1007/978-3-032-08163-6_1

Microbial Biomineralisation in Living Artefacts for Regenerative Ecologies: An Overview and Design Pathways

Auteurs: Verindi Vekemans, Stefano Parisi, Joana Martins, Jun Wu, Marie-Eve Aubin-Tam, Elvin Karana
Publié dans: What's Around Design?, 2026
Éditeur: Springer Nature Switzerland
DOI: 10.1007/978-3-032-11584-3_1

Resultats de projets

Livrables

Publications

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