Project description
Deep-tech discovery platform for tailor-made enzybiotics
Overuse of antibiotics, particularly in agriculture, has led to the emergence of antibiotic resistance. Furthermore, lack of investment in the discovery of new antibiotics has meant bacterial infections are on the rise due to a lack of effective remedies. Enzybiotics, bacteriolytic enzymes that in a very effective and selective way eliminate bacteria, including antibiotic-resistant strains, and display very low resistance prevalence, is one of a number of promising new approaches. The EU-funded ENZYBIOTX project provides a deep-tech discovery platform for tailor made-enzybiotics, targeting specific pathogenic bacteria to address the need for alternative development of antimicrobials. The proprietary technology allows the company to collaborate with clients to create specific enzymes and perform all the tests needed to adjust their properties before introducing them into a final product.
Objective
Since the discovery of penicillin people were living in justified confidence that available antibiotics can cure any bacterial infections. Emerging antibiotic resistance was usually overcome by treatment with new generation of antibiotics, but during last decades bacteria are clearly winning this race. Overuse of antibiotics, particularly in agriculture, and lack of investments in discovery of new antibiotics lead us to situation when increasing number of bacterial infections cannot be cured due to lack of effective remedy. Antibiotic resistance surveillance revealed rising antibiotic resistance around the world. WHO predicts that if no appropriate actions are taken by 2050 antibiotic resistance will be responsible even for 10 mln deaths every year. To address this urgent medical need new antibiotics and alternative methods of combating antibiotic resistant bacteria are needed. One of the new approaches which is getting more and more interests among academic and industrial research groups are enzybiotics, bacteriolytic enzymes that in a very effective and selective way eliminate bacteria, including antibiotic resistant strains, at the same time displaying very low resistance prevalence. Enzybiotx provides a deep-tech platform for tailor made-enzybiotics targeting specific bacteria. Our company has developed the platform for design and generation of new enzybiotcs to target pathogenic bacteria of interest as an answer to the need of alternative antimicrobials development. The company in collaboration with potential clients is able to prepare tailor-made enzybiotics which target pathogens and in collaboration with the client, perform all tests needed to adjust enzyme’s properties to be able to introduce them to the final products.
The founders of the company are experienced academics who have gathered unique expertise in isolation and characterisation of new enzybiotics.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- agricultural sciences agriculture, forestry, and fisheries agriculture
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.2 - European innovation ecosystems
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-CSA - HORIZON Coordination and Support Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIE-2021-SCALEUP-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
81-521 Gdynia
Poland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
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