Breaking the barrier - An integrated multidisciplinary approach to kill Gram-negative bacteria through existing antibiotics by making their outer membrane permeable

Project Information

BREAKthrough

Grant agreement ID: 101072632

DOI

10.3030/101072632

EC signature date 14 July 2022

Start date 1 January 2023

End date 30 September 2027

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 618 488,80

Coordinated by

UNIVERSITE CATHOLIQUE DE LOUVAIN
Belgium

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

BREAKthrough Science Days
BREAKthrough Industry & Business Days

BREAKthrough Industry Business Days

Websites, patent fillings, videos etc. (1)

Project website

Publications

Peer reviewed articles (3)

Breaking Barriers: Exploiting Envelope Biogenesis and Stress Responses to Develop Novel Antimicrobial Strategies in Gram-Negative Bacteria

Author(s): Renu Bisht, Pierre D. Charlesworth, Paola Sperandeo, Alessandra Polissi
Published in: Pathogens, Issue 13, 2025, ISSN 2076-0817
Publisher: MDPI AG
DOI: 10.3390/pathogens13100889

Peptidoglycan Remodeling in Gram-Negative Bacteria: From Stress Adaptation to Antibiotic Tolerance and Therapeutic Targeting

Author(s): Theresa Strohhammer, Alessandra M. Martorana, Alessandra Polissi
Published in: Antibiotics, Issue 15, 2026, ISSN 2079-6382
Publisher: MDPI AG
DOI: 10.3390/ANTIBIOTICS15080815

Overproduction of β-barrel outer membrane proteins in Escherichia coli BL21(DE3) induces hypervesiculation

Author(s): Saloni Sahu, Gregory Koningstein, Catalin Bunduc, Nicole van der Wel, Joen Luirink, Peter van Ulsen
Published in: Extracellular Vesicles and Circulating Nucleic Acids, Issue 6, 2025, ISSN 2767-6641
Publisher: OAE Publishing Inc.
DOI: 10.20517/EVCNA.2025.27