DNA replication at the heart of cell fate decisions and cancer development

Project Information

RepliFate

Grant agreement ID: 101072903

DOI

10.3030/101072903

EC signature date 14 July 2022

Start date 1 October 2022

End date 30 September 2026

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 650 312,80

Coordinated by

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (2)

Webpage, image and social media kick-off

Development of the Webpage and image of the network. Kick-off of the activities in social-media.

Creation of motion video

Development of a motion video by the fellows with the help of ScienSeed to showcase the actions of the network

Publications

Peer reviewed articles (4)

Blood Cancer Journal

Author(s): María Castejón-Griñán; Eliene Albers; Lucía Simón-Carrasco; Paula Aguilera; Mauro Sbroggio; David Pladevall-Morera; Andreas Ingham; Ernest Lim; Alba Guillen-Benitez; Elena Pietrini; Michael Lisby; Ian D. Hickson; Andres J. Lopez-Contreras
Published in: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-15 (2024), 2024, ISSN 2044-5385
Publisher: Nature
DOI: 10.1038/s41408-024-00979-y

DNA polymerase α/primase extraction from chromatin by VCP/p97 restricts ATR activation during unperturbed DNA replication

Author(s): Sara Rodríguez-Acebes; Rodrigo Martín-Rufo; Alicia Gómez-Moya; Scott B. Churcher; Alejandro Fernández-Llorente; Guillermo de la Vega-Barranco; Alejandra Perona; Pilar Oroz; Elena Martín-Doncel; Luis Ignacio Toledo; Juan Méndez; Emilio Lecona
Published in: Nature Communications, 2025
Publisher: NATURE
DOI: 10.1038/S41467-025-60077-W

Slow RNAPII elongation enhances naive pluripotency rewiring while maintaining high replication fork speed

Author(s): Sara Martín-Vírgala, Joana Segura, Alicia Gallego, Ran Tong, Sara Tur-Gracia, Jesús Rafael Rodriguez-Aguilera, Biswajit Das, Javier Isoler-Alcaraz, Carlos Gallego-García, Shraddha Shinde, Magdalena M. Maslon, Andrei Chabes, Lothar Schermelleh, María Gómez
Published in: Science Advances, Issue 12, 2026, ISSN 2375-2548
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADZ6211

PARP1-dependent DNA-protein crosslink repair

Author(s): Zita Fábián, Ellen S. Kakulidis, Ivo A. Hendriks, Ulrike Kühbacher, Nicolai B. Larsen, Marta Oliva-Santiago, Junhui Wang, Xueyuan Leng, A. Barbara Dirac-Svejstrup, Jesper Q. Svejstrup, Michael L. Nielsen, Keith Caldecott, Julien P. Duxin
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41467-024-50912-x