Objective Recent advances in the field of synthetic biology offer an unprecedented opportunity for next-generation biosensors characterized by programmability, low-cost and by a sensitivity and specificity unmet by conventional sensors. Leveraging the rich toolset of synthetic biology, we can now not only build better biosensors but also analytical tools that can sense and discern complex analyte profiles, such as a panel of biomarkers indicative of a certain disease status. These cell-free biosensors developed within the SYNSENSO research program will be transformative for many domains of research and innovation, ranging from in-vitro diagnostics to health, environmental and bioprocess monitoring. Our ambition is to provide a game change in biosensing by combining cell-free synthetic biology with molecular sensor design. The SYNSENSO European doctoral network focuses on the construction of novel programmable ligand-responsive elements and the construction of cell-free computing circuits that can integrate molecular signals from those elements. Together the two components will make up the next generation of combinatorial biosensors that can sense signals and compute a response to them. SYNSENSO aims for a modular approach where different responsive elements can be composed with different computing circuits enabling fast construction of suitable sensors for new application domains. SYNSENSO brings together academic and industry leaders from the fields of synthetic biology, molecular sensor design and DNA nanotechnology. Our industry partners will provide a unique ecosystem for ten doctoral candidates of this network. Together with the external advisory board including experts from medical diagnostics they will work on concrete case studies for clinically relevant analytes. The SYNSENSO training program will empower them to perform world-class research and become academic or industry leaders in this new emerging field at the intersection of synthetic biology and biosensors. Fields of science engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsnatural sciencesbiological sciencessynthetic biologynatural sciencesbiological sciencesgeneticsDNAengineering and technologynanotechnologynatural sciencesbiological sciencesecologyecosystems Keywords Synthetic biology cell-free biosensors DNA nanotechnology gene circuits molecular computing biocomputing in-vitro diagnostics environmental monitoring biomarkers point-care-diagnostics Programme(s) HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme Topic(s) HORIZON-MSCA-2021-DN-01-01 - MSCA Doctoral Networks 2021 Call for proposal HORIZON-MSCA-2021-DN-01 See other projects for this call Funding Scheme HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks Coordinator TECHNISCHE UNIVERSITAT DARMSTADT Net EU contribution € 781 617,60 Address KAROLINENPLATZ 5 64289 Darmstadt Germany See on map Region Hessen Darmstadt Darmstadt, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Participants (5) Sort alphabetically Sort by Net EU contribution Expand all Collapse all TECHNISCHE UNIVERSITEIT EINDHOVEN Netherlands Net EU contribution € 548 740,80 Address GROENE LOPER 3 5612 AE Eindhoven See on map Region Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA Italy Net EU contribution € 259 437,60 Address VIA MOREGO 30 16163 Genova See on map Region Nord-Ovest Liguria Genova Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA Italy Net EU contribution € 518 875,20 Address VIA CRACOVIA 50 00133 Roma See on map Region Centro (IT) Lazio Roma Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data DYNAMIC BIOSENSORS GMBH Germany Net EU contribution € 260 539,20 Address PERCHTINGER STRASSE 8/10 81379 Munich See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data ULISSE BIOMED Italy Net EU contribution € 259 437,60 Address VIA CAVOUR 20 33100 Udine See on map Region Nord-Est Friuli-Venezia Giulia Udine Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partners (8) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Abvance Biotech srl Spain Net EU contribution € 0,00 Address Av. Reina Victoria 32 28003 Madrid See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data ACCELOPMENT SCHWEIZ AG Switzerland Net EU contribution € 0,00 Address SEEFELDSTRASSE 198 8008 ZURICH See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data LENIOBIO GMBH Germany Net EU contribution € 0,00 Address ERKRATHER STRASSE 401 40231 Dusseldorf See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nordrhein-Westfalen Düsseldorf Düsseldorf, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG Germany Net EU contribution € 0,00 Address Darmstädter Straße 34-36 64673 Zwingenberg See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Hessen Darmstadt Bergstraße Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Nuclera Nucleics Ltd United Kingdom Net EU contribution € 0,00 Address 137 Cambridge Science Park, Milton Road CB4 0GD CAMBRIDGE See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region East of England East Anglia Cambridgeshire CC Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data BIOMERIEUX SA France Net EU contribution € 0,00 Address Chemin de l'Orme 69280 Marcy l'Etoile See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE United Kingdom Net EU contribution € 0,00 Address SOUTH KENSINGTON CAMPUS EXHIBITION ROAD SW7 2AZ LONDON See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Department of Biology, University of Naples Federico II Italy Net EU contribution € 0,00 Address via Cinthia 7 80121 Naples See on map Region Sud Campania Napoli Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data
