Project description
Innovative platforms for high-quality recombinant protein production
Secreted high-quality recombinant proteins, especially industrial enzymes and therapeutic proteins (biotherapeutics) are significant for healthcare and a sustainable bio-based economy. However, recombinant protein production is mainly carried out in high-income countries, resulting in inequality in the biotechnology sector. The EU-funded greenerRPP project will address the rapidly emerging issue of 'sustainability' in the European biotechnology industry by developing powerful new microbial and mammalian cell platforms that produce recombinant proteins in unusually high quantities and unparalleled quality. The project will improve yield and process design to increase the industry's effectiveness and reduce high levels of waste and reduce energy and raw material costs in countless industrial and domestic settings.
Objective
The greenerRPP project aims to markedly enhance the EUs capacity for the production of secreted high-quality recombinant proteins, especially industrial enzymes and therapeutic proteins (biotherapeutics). The combined markets are in excess of $330 billion p.a. and the products are of massive significance for healthcare and a sustainable bio-based economy. greenerRPP will address urgent problems in these industries, such as difficult-to-express proteins and the rapidly-emerging issue of 'sustainability' in the European biotechnology industry. It will deliver improvements in yield and process design that increase the industry's effectiveness while simultaneously reducing high current levels of waste. It will deliver industrial enzymes that reduce energy and raw material costs in countless industrial and domestic settings. To achieve this, we will develop powerful new microbial and mammalian cell platforms that produce recombinant proteins in unusually high quantities and in unparalleled quality, and bring to market a suite of super-producing platforms.
A comprehensive training programme will equip greenerRPP ESRs with the interdisciplinary and intersectoral skills required to be future leaders in these industries, while emphasising sustainability and gender-diversity dimension principles at every level. Finally, the programme addresses the stark global inequality in this biotechnology sector: recombinant protein production is largely carried out in (or outsourced by) high-income countries, placing low/middle income countries at a massive disadvantage. greenerRPP includes a series of South East Asian Institutions as Associated Partners, to develop a global network with a knowledge exchange-secondment programme that boosts these countries' own manufacturing programmes. greenerRPP ESRs will thus enhance a European industrial sector that has never been more important to society, while making it 'greener' and reaching out to lower income countries.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-DN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
9713 GZ Groningen
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.