Green and digital continuous-flow pharmaceutical manufacturing

Project Information

GreenDigiPharma

Grant agreement ID: 101073089

DOI

10.3030/101073089

EC signature date 6 July 2022

Start date 1 January 2023

End date 31 December 2026

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 605 881,60

Coordinated by

POLITECNICO DI MILANO
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (1)

Website

Website, Twitter and Instagram accounts

Publications

Peer reviewed articles (11)

Electrosynthesis of Aryliminophosphoranes in Continuous Flow

Author(s): Rodrigo Costa e Silva, Clara Vega, Morgan Regnier, Luca Capaldo, Lars Wesenberg, Grace Lowe, Kleber Thiago de Oliveira, Timothy Noël
Published in: Advanced Synthesis & Catalysis, Issue 366, 2025, ISSN 1615-4150
Publisher: Wiley
DOI: 10.1002/ADSC.202300635

Rapid and scalable photocatalytic C(sp2)–C(sp3) Suzuki−Miyaura cross-coupling of aryl bromides with alkyl boranes

Author(s): Ting Wan, Luca Capaldo, Jonas Djossou, Angela Staffa, Felix J. de Zwart, Bas de Bruin, Timothy Noël
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-48212-5

Flow Electroreductive Nickel‐Catalyzed Cyclopropanation of Alkenes Using <i>gem</i>‐Dichloroalkanes

Author(s): Morgan Regnier, Clara Vega, Dimitris I. Ioannou, Zhenyu Zhang, Timothy Noël
Published in: Angewandte Chemie International Edition, 2025, ISSN 1433-7851
Publisher: Wiley
DOI: 10.1002/ANIE.202500203

Sustainability and Techno-Economic Assessment of Batch and Flow Chemistry in Seven Industrial Pharmaceutical Processes

Author(s): Mert Can Ince, Brahim Benyahia, Gianvito Vilé
Published in: ACS Sustainable Chemistry &amp; Engineering, 2025, ISSN 2168-0485
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACSSUSCHEMENG.4C09289

Enhancing electrochemical reactions in organic synthesis: the impact of flow chemistry

Author(s): Morgan Regnier, Clara Vega, Dimitris I. Ioannou, Timothy Noël
Published in: Chemical Society Reviews, Issue 53, 2024, ISSN 0306-0012
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4CS00539B

Visible light-induced halogen-atom transfer by N-heterocyclic carbene-ligated boryl radicals for diastereoselective C(sp³)–C(sp²) bond formation

Author(s): Luca Capaldo, Ting Wan, Robin Mulder, Jonas Djossou, Timothy Noël
Published in: Chemical Science, Issue 15, 2024, ISSN 2041-6520
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4SC02962C

1‐Oxa‐2,6‐Diazaspiro[3.3]heptane as a New Potential Piperazine Bioisostere – Flow‐Assisted Preparation and Derivatisation by Strain‐Release of Azabicyclo[1.1.0]butanes

Author(s): Elena Graziano, Philipp Natho, Michael Andresini, Fabrizio Mastrolorito, Iktedar Mahdi, Ernesto Mesto, Marco Colella, Leonardo Degennaro, Orazio Nicolotti, Renzo Luisi
Published in: Advanced Synthesis &amp; Catalysis, 2024, ISSN 1615-4150
Publisher: Wiley
DOI: 10.1002/ADSC.202400781

A Practical Guide to SuFEx Chemistry: An Overview of S(VI)-SuFEx Linkers and Their Reactivity

Author(s): Defne Serbetci, Laura Marraffa, Renzo Luisi, Philipp Natho, Michael Andresini
Published in: Synthesis, 2024, ISSN 0039-7881
Publisher: Georg Thieme Verlag KG
DOI: 10.1055/A-2410-2039

Continuous Flow Decarboxylative Monofluoroalkylation Enabled by Photoredox Catalysis

Author(s): Francesco Pasca, Yuri Gelato, Michael Andresini, Defne Serbetci, Philipp Natho, Giuseppe Romanazzi, Leonardo Degennaro, Marco Colella, Renzo Luisi
Published in: JACS Au, 2025, ISSN 2691-3704
Publisher: American Chemical Society (ACS)
DOI: 10.1021/JACSAU.4C00902

Sustainable upgrading of glycerol into glycidol and its derivatives under continuous-flow conditions

Author(s): Alessandra Sivo, Ilaria Montanari, Mert Can Ince, Gianvito Vilé
Published in: Green Chemistry, Issue 26, 2024, ISSN 1463-9262
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4GC01565G

Synthesis of Aza‐S(VI) Fluorides and Primary Sulfonimidamides from Sulfinylamines

Author(s): Michael Andresini, Laura Marraffa, Defne Şerbetçi, Philipp Natho, Marco Colella, Leonardo Degennaro, Renzo Luisi
Published in: Advanced Synthesis &amp; Catalysis, Issue 367, 2025, ISSN 1615-4150
Publisher: Wiley
DOI: 10.1002/ADSC.202400908