Reconstructing enzymes for novel nitrogen-nitrogen bond forming chemistry

Project Information

ReCNNSTRCT

Grant agreement ID: 101075934

DOI

10.3030/101075934

EC signature date 8 December 2022

Start date 1 January 2023

End date 31 December 2027

Funded under

• European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

RIJKSUNIVERSITEIT GRONINGEN
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type <scp>III</scp> polyketide synthases

Author(s): Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger
Published in: The FEBS Journal, 2025, ISSN 1742-464X
Publisher: Wiley
DOI: 10.1111/FEBS.70376

Pioneering Women Shaping the Field of Biocatalysis

Author(s): Benítez-Mateos, Ana I.; Paul, Caroline E.; Schmidt, Sandy; Contente, Martina Letizia
Published in: ChemCatChem, 2025, ISSN 1867-3899
Publisher: Wiley
DOI: 10.3929/ETHZ-B-000731791

Access to Nitrogen–nitrogen Bond-Containing Heterocycles Through Substrate Promiscuity of Piperazate Synthases

Author(s): Yongxin Li, Angelina Osipyan, Niels A.W. de Kok, Simon Schröder, Maria Founti, Peter Fodran, Ronald van Merkerk, Artur Maier, Dirk Tischler, Sandy Schmidt
Published in: ACS Catalysis, Issue 15, 2025, ISSN 2155-5435
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACSCATAL.5C01237

Recent Developments and Challenges in the Enzymatic Formation of Nitrogen–Nitrogen Bonds

Author(s): Charitomeni Angeli, Sara Atienza-Sanz, Simon Schröder, Annika Hein, Yongxin Li, Alexander Argyrou, Angelina Osipyan, Henrik Terholsen, Sandy Schmidt
Published in: ACS Catalysis, 2024, ISSN 2155-5435
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACSCATAL.4C05268

Cell-free chemoenzymatic cascades with bio-based molecules

Author(s): Henrik Terholsen, Sandy Schmidt
Published in: Current Opinion in Biotechnology, 2024, ISSN 1879-0429
Publisher: Elsevier
DOI: 10.1016/j.copbio.2023.103058

Nitroreductase-triggered indazole formation

Author(s): Henrik Terholsen, Lisa Medema, Elizaveta Chernyshova, Alejandro Prats Luján, Gerrit J. Poelarends, Sandy Schmidt
Published in: ChemRxiv, 2025, ISSN 2573-2293
Publisher: Cambridge University Press
DOI: 10.26434/CHEMRXIV-2025-2HS17

Nitroreductase-triggered indazole formation

Author(s): Henrik Terholsen, Lisa Medema, Elizaveta Chernyshova, Alejandro Prats Luján, Gerrit J. Poelarends & Sandy Schmidt
Published in: Nature Communications, 2026, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/S41467-026-68926-Y