Chromatin re-organization in response to replication stress

Project Information

ChOReS

Grant agreement ID: 101078750

DOI

10.3030/101078750

EC signature date 2 February 2023

Start date 1 March 2023

End date 29 February 2028

Funded under

• European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

Drafting of Data Management Plan

Publications

Peer reviewed articles (7)

H2BK120ub and its reader RNF169 sequentially regulate replication fork remodeling and stability

Author(s): Filip D Duzanic, Vaishnavi Mohana-Natarajan, Samuele Fisicaro, Collin Bakker, Moses Aouami, Gabriel Amaral, Massimo Lopes, Nitika Taneja, Lorenza Penengo
Published in: The EMBO Journal, Issue 44, 2026, ISSN 1460-2075
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S44318-025-00602-1

Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress

Author(s): Maxime Galloy, Andréanne Blondeau, Élodie Vion, Daein Kim, Collin A. Bakker, Vincent Gaggioli, Mélissa Thomas, Élise G. Lavoie, Isabelle Marois, Alberto David Delgado Monterroso, Jean-Yves Masson, Nitika Taneja, Kyle M. Miller, Alexandre Maréchal, Amélie Fradet-Turcotte
Published in: Molecular Cell, Issue 85, 2026, ISSN 1097-2765
Publisher: Elsevier BV
DOI: 10.1016/J.MOLCEL.2025.07.013

Enhancing quantitative imaging to study DNA damage response: A guide to automated liquid handling and imaging

Author(s): Calvin Shun Yu Lo, Nitika Taneja, Arnab Ray Chaudhuri
Published in: DNA Repair, Issue 144, 2026, ISSN 1568-7864
Publisher: Elsevier BV
DOI: 10.1016/J.DNAREP.2024.103769

Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels

Author(s): Veronica Cherdyntseva, Joanna Paulson, Daniel González-Acosta, Patricia Ubieto-Capella, Melani Rodrigues, Moses Aouami, Selin Adakli, Jean-Philippe Gagné, Collin Bakker, Guy G. Poirier, Nitika Taneja, Massimo Lopes
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-66098-9

Replication-stress-induced chromatin loops protect fork stability

Author(s): Vincent Gaggioli, Kaustav Sengupta, Ashutosh Choudhury, Joanna Paulson, Raviprasad Kuthethur, Collin Bakker, Jialun Li, Calvin S. Y. Lo, Alex Whale, Jeroen van den Berg, Leire Asua Intxausti, Noelia Gil-Lanza, Iván Galván-Femenía, Eleni Maria Manolika, Sangavi Eswaran, Hina N. Khan, Estel Ferré, Gregorie Stik, Alexander van Oudenaarden, Argyris Papantonis, Jonathan Houseley, Sriram Sridharan, Arnab Ray Chaudhuri, Aleix Bayona-Feliu, Nitika Taneja
Published in: Nature, 2026, ISSN 0028-0836
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41586-026-10695-1

Fencing the genome: ubiquitin signaling restricts heterochromatin spread

Author(s): Collin Bakker, Joanna Paulson, Nitika Taneja
Published in: Signal Transduction and Targeted Therapy, Issue 10, 2025, ISSN 2059-3635
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41392-025-02349-X

Nature Cell Biology

Author(s): Vincent Gaggioli; Calvin S. Y. Lo; Nazaret Reverón-Gómez; Zuzana Jasencakova; Heura Domenech; Hong Nguyen; Simone Sidoli; Andrey Tvardovskiy; Sidrit Uruci; Johan A. Slotman; Yi Chai; João G. S. C. Souto Gonçalves; Eleni Maria Manolika; Ole N. Jensen; David Wheeler; Sriram Sridharan; Sanjiban Chakrabarty; Jeroen Demmers; Roland Kanaar; Anja Groth; Nitika Taneja
Published in: Nature Cell Biology, 2023, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/S41556-023-01167-Z