Project description
Advanced research on osteoarthritis in Lithuania
Tools used currently to treat degenerative and inflammatory arthritis are not satisfactory. The application of specific disease biomarkers is needed because they increase the success rate of drug development programmes and accelerate the availability of new therapeutics. Partnerships providing access to tissue banks, data, cell lines, biomarkers, patients and funding are essential for new treatments. The EU-funded TWINFLAG project is an advanced twinning aiming to improve the capacities of the Centre for Innovative Medicine (IMC), Lithuania, in the field of extracellular vesicles (EVs), flow cytometry, and biobanking. The twinning with UCD (Ireland) and INIBIC (Spain) will implement excellence in the translational research of arthritis treatment and EV-based biomarker development, innovation, and research management.
Objective
TWINFLAG is an advanced research consortium consisting of top-class institutions in the field of extracellular vesicles (EVs), flow cytometry and biobanking. The main objective of TWINFLag is to improve capacities of IMC in Lithuania, to implement the excellence in translational research of arthritis treatment and extracellular vesicle (EV)-based biomarker development, innovation and research management. For this purpose, the consortium gathered leading academic institutions in the field of biomedical sciences from Ireland (UCD) and Spain (INIBIC) which will seek to raise the research profile of IMC. The consortium partners will share their knowledge during organized schools, short term visits and seminars, will implement a small scale research for a personalized therapeutic approach focusing on major research interests of IMC – degenerative and inflammatory arthritis. Currently available tools for the disease-modifying therapy of both rheumatoid and osteo- arthritis are not satisfactory, which is highly associated with the lack of specific and sensitive disease biomarkers. The need for the application specific disease biomarkers has been emphasized as they increase the success rate of drug development programmes and thereby accelerate the availability of new therapeutics. Partnerships that provide access to tissue banks, data, cell lines, biomarkers, patients and funding are essential for the development of novel therapeutics. Therefore, this three partner consortium identified the demand to develop an innovative joint-research strategy comprising application of novel therapeutics for arthritis, associated with the development of precision biomarkers for monitoring the efficacy of this treatment. The results of this project will contribute to increased attractiveness of IMC, retention of research talents and mobilization of national and European resources for strategic investments, as well as foster networking and business ideas.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.4.1 - Widening participation and spreading excellence
MAIN PROGRAMME
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HORIZON.4.1.2 - Twinning
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-CSA - HORIZON Coordination and Support Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-WIDERA-2021-ACCESS-03
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
LT-08406 Vilnius
Lithuania
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.