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Valorising magnetometry in cells

Objective

Magnetic resonance spectroscopy (NMR or ESR) and magnetic resonance imaging (MRI) are widely used. However, magnetic resonance signals are low in energy and thus difficult to detect. These techniques are expensive and typically only offer millimeter down to micrometer resolution. Diamond magnetometry potentially offers a solution. The technique is based on a quantum effect and allows even the detection of single electron spins. While the technique is already used for a few years in physics, during my ERC project this powerful tool was utilised for the first time to measure metabolic activity in living cells.
The aim of this project is to explore the commercial potential of these results and - if it is deemed feasible - found a start-up company for exploitation.
As a first application we will investigate free radical generation. These molecules play a key role in many biological processes including cell communication, immune responses or ageing. Additionally, they are an indicator for stress and thus play a role in many diseases including cancer, cardiovascular diseases or viral and bacterial infections. Despite their relevance and the fact that free radical generation is often an early sign of disease, they are rarely used as biomarkers since they are notoriously difficult to measure. In this project we will build a prototype (to be patented) that can be used for demonstrations to customers. This will be done on close collaboration with a user committee in order to meet the customer expectations. To demonstrate the usefulness to customers for diagnosis we will conduct test measurements . Further, we will assess whether a business model based on a product or based on services or a hybrid business model containing both is most promising.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2022-POC2

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Host institution

ACADEMISCH ZIEKENHUIS GRONINGEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 150 000,00
Address
HANZEPLEIN 1
9713 GZ Groningen
Netherlands

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Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Beneficiaries (1)

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