Transforming bone cancer therapy with composite biomaterials encapsulating plasma-generated RONS

Project Information

TRANSFORMER

Grant agreement ID: 101082096

DOI 10.3030/101082096

Project closed

EC signature date 8 July 2022

Start date 1 November 2022

End date 30 April 2024

Funded under

• European Research Council (ERC)

Total cost No data

EU contribution € 150 000,00

Coordinated by

UNIVERSITAT POLITECNICA DE CATALUNYA
Spain

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Cold plasma and inhibition of STAT3 selectively target tumorigenicity in osteosarcoma

Author(s): J. Tornín, M. Mateu-Sanz, V. Rey, D. Murillo, C. Huergo, B. Gallego, A. Rodriguez, R. Rodríguez, C. Canal.
Published in: Redox Biology, Issue Volume 62,102685, 2023, ISSN 2213-2317
Publisher: Elsevier
DOI: 10.1016/j.redox.2023.102685

Does non-thermal plasma modify biopolymers in solution? A chemical and mechanistic study for alginate

Author(s): F. Tampieri, A. Espona-Noguera, C. Labay, M.-P. Ginebra, M. Yusupov, A. Bogaerts, C. Canal.
Published in: Biomater. Sci., Issue 11, 4845, 2023, ISSN 2047-4849
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3bm00212h

Oxidation of lactate to pyruvate mediates the cytotoxic potential of physical plasma-treated saline solutions in ovarian cancer

Author(s): C. Bucci, F. Tampieri, M.Mateu-Sanz, R. Laurita, V. Colombo, C. Canal.
Published in: Plasma Processes and Polymers, Issue Volume 20, Issue 12 (e2300093), 2023, ISSN 1612-8869
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ppap.202300093

Engineering alginate-based injectable hydrogels combined with bioactive polymers for targeted plasma-derived oxidative stress delivery in osteosarcoma therapy

Author(s): A. Espona, F. Tampieri, C. Canal.
Published in: International Journal of Biological Macromolecules, Issue Volume 257, Part 2, 128841, 2024, ISSN 0141-8130
Publisher: Elsevier BV
DOI: 10.1016/j.ijbiomac.2023.128841

Injectable Plasma-Treated Alginate Hydrogel for Oxidative Stress Delivery to Induce Immunogenic Cell Death in Osteosarcoma

Author(s): M. Živanić, A. Espona-Noguera, H. Verswyvel, E. Smits, A. Bogaerts, A. Lin, C. Canal.
Published in: Adv. Funct. Mater., Issue 34, 2312005, 2024, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202312005

Cold plasma-treated medium preferentially eliminates doxorubicin-resistant osteosarcoma cells

Author(s): J. Tornín, B. Gallego, V. Rey, D. Murillo, C. Huergo, A. Rodríguez, C. Canal, R. Rodríguez.
Published in: Free Radical Biology and Medicine, Issue Volume 209, Part 1, 127-134, 2023, ISSN 0891-5849
Publisher: Elsevier
DOI: 10.1016/j.freeradbiomed.2023.10.394

Thesis and dissertations (2)

Effects of cold atmospheric plasmas on biomaterials: hydrogels and composites with calcium phosphates.

Author(s): Solé Martí, X.
Published in: 2023
Publisher: UPCommons

Caracterización técnica de vehículos y biomateriales tratados con plasma de acuerdo con regulatoria

Author(s): Fernández Gutiérrez, Pablo
Published in: 2023
Publisher: UPC Commons

Intellectual Property Rights

Patent (2)

PLASMA-TREATED HYDROGEL COMPOSITIONS AND USES THEREOF

Application/Publication number: EP 21732077
Date: 2021-06-17
Applicant(s): UNIVERSITAT POLITECNICA DE CATALUNYA

COMBINED THERAPY AGAINST CANCER

Application/Publication number: EP 21807156
Date: 2021-11-23
Applicant(s): UNIVERSITAT POLITECNICA DE CATALUNYA