In recent years, numerous EIP-AGRI Operational Groups (OGs) have generated extensive knowledge on technologies, products, recommendations, and best practices in nutrient management. Despite this, the adoption of these innovations by practitioners in the agri-livestock sector has been significantly lower than anticipated. The underutilization of these advanced nutrient management strategies highlights a critical gap between the development of knowledge and its practical application. The NUTRI-KNOW project aims to address this by enhancing the impact of EIP-AGRI OG innovations on nutrient management, with the broader goal of modernising and dynamising the agricultural sector. The project seeks to achieve this by collecting, translating, and sharing practical, easily understandable knowledge to ensure its effective adoption by farmers, practitioners, and other relevant stakeholders. NUTRI-KNOW strategically involves 12 EIP-AGRI OGs from four Member States—Spain, Italy, Belgium, and Ireland. These projects cover the entire nutrient management value chain, including livestock farming, storage systems, processing technologies, fertilizer production, transport, and application. NUTRI-KNOW’s methodology comprises five key steps (image 1): step 1) comprehensive data collection and analysis of outcomes from the engaged OGs; step 2) multi-approach baseline analysis to establish a robust understanding of the current context; step 3) consolidation and translation of knowledge into practitioner-friendly language; step 4) dissemination and transfer of practice-oriented materials through channels commonly used by farmers; and step 5) connecting stakeholders and regions. By implementing this methodology, NUTRI-KNOW aims to achieve several significant impacts. First, it seeks to bridge the knowledge-to-application gap, ensuring that the wealth of knowledge generated by EIP-AGRI OGs is effectively adopted and utilized in the agricultural sector. This will help practitioners to better apply advanced nutrient management strategies, enhancing overall efficiency and productivity. Second, NUTRI-KNOW intends to develop a Results Amplification Methodology. This will provide guidelines for effectively scaling and broadening project outcomes across various themes, ensuring that the benefits of innovative practices are maximized and widely distributed. Third, the project aims to foster a sustainable and dynamic agricultural sector by promoting sustainable practices and innovations. These efforts will enhance the vitality and productivity of agriculture, contributing to long-term environmental and economic benefits. Ultimately, NUTRI-KNOW aspires to transform the agricultural landscape by facilitating the practical application of advanced nutrient management strategies. This transformation will lead to a more modern, dynamic, and sustainable agricultural sector, capable of meeting current and future challenges effectively.