Advanced epigenetics studies to increase the research and innovations capacity of the Roumen Tsanev Institute of Molecular Biology of the Bulgarian Academy of Sciences

Informations projet

AEGIS-IMB

N° de convention de subvention: 101086923

DOI

10.3030/101086923

Date de signature de la CE 19 Octobre 2022

Date de début 1 Mars 2023

Date de fin 29 Février 2028

Financé au titre de

• Widening participation and spreading excellence

Coût total

€ 2 498 990,00

Contribution de l’UE

€ 2 498 990,00

Coordonné par

ROUMEN TSANEV INSTITUTE OF MOLECULAR BIOLOGY BULGARIAN ACADEMY OF SCIENCES
Bulgaria

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (4)

D6.1 - Plan of dissemination, exploitation and communication activities

Detailed plan and description of dissemination, exploitation of results and communication activities.

D1.1 - Handbook, outlining management structures and procedures

Project management handbook, outlining the final management structures and procedures implemented.

D2.3 - Working principles and formation of the ERA Chair group

ERA Chair working principles and formation of the ERA Chair group.

D2.4 - ERA Chair group formation

Report on the formation of the ERA Chair group.

Data Management Plan (1)

D1.2 - Data management plan

This deliverable consists of the data management plan of AEGIS-IMB.

Publications

Peer reviewed articles (7)

Synergistic Upregulation of Extracellular Vesicles and Cell-Free Nucleic Acids by Chloroquine and Temozolomide in Glioma Cell Cultures

Auteurs: Aleksander Emilov Aleksandrov, Banko Ivaylov Bankov, Vera Lyubchova Djeliova, Georgi Georgiev Antov, Svetozar Stoichev, Roumyana Silvieva Mironova, Dimitar Borisov Iliev
Publié dans: International Journal of Molecular Sciences, Numéro 26, 2025, ISSN 1422-0067
Éditeur: MDPI AG
DOI: 10.3390/IJMS26199692

Molecular Mechanism of Nucleosome Recognition by the Pioneer Transcription Factor Sox

Auteurs: Burcu Ozden; Ramachandran Boopathi; Ayşe Berçin Barlas; Imtiaz N. Lone; Jan Bednar; Carlo Petosa; Seyit Kale; Ali Hamiche; Dimitar Angelov; Stefan Dimitrov; Ezgi Karaca
Publié dans: "Journal of Chemical Information and Modeling, 2023, 63 (12), pp.3839-3853. ⟨10.1021/acs.jcim.2c01520⟩", 2023, ISSN 1549-960X
Éditeur: ACS Publications
DOI: 10.1021/acs.jcim.2c01520

Nucleic Acids Research

Auteurs: Edwige Belotti, Nicolas Lacoste, Arslan Iftikhar, Thomas Simonet, Christophe Papin, Alexis Osseni, Nathalie Streichenberger, Pierre-Olivier Mari, Emmanuelle Girard, Mohamed Graies, Giuseppina Giglia-Mari, Stefan Dimitrov, Ali Hamiche,Laurent Schaeffer
Publié dans: Nucleic Acids Research, 2024, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkae020

Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1-4

Auteurs: Abed Alkarem Abu Alhaija; Imtiaz Nisar Lone; Esin Ozkuru Sekeroglu; Tugce Batur; Dimitar Angelov; Dimitrov Stefan; Ali Hamiche; Elif Nur Firat Karalar; Muhammed Erdem Ercan; Tamer Yagci; Hani Alotaibi; Muhammed Kasim Diril
Publié dans: FEBS Open Bio, ISSN 2211-5463
Éditeur: Wiley
DOI: 10.1002/2211-5463.13750

Monogenic forms of inflammatory bowel disease: Genetic mechanisms, models, and clinical implications

Auteurs: Amirhossein Ghorbanpour, Pejman Rohani, Shabnam Shahrokh, Georges Dimitrov, Mehdi Totonchi, Stefan Dimitrov
Publié dans: Molecular Medicine, Numéro 32, 2026, ISSN 1528-3658
Éditeur: Springer Science and Business Media LLC
DOI: 10.1186/S10020-026-01424-5

The CENP-A nucleosome: where and when it happens during the inner kinetochore’s assembly

Auteurs: Seyit Kale, Ramachandran Boopathi, Edwige Belotti, Imtiaz Nisar Lone, Mohamed Graies, Maria Schröder, Maria Petrova, Christophe Papin, Jan Bednar, Iva Ugrinova, Ali Hamiche, Stefan Dimitrov
Publié dans: Trends in Biochemical Sciences, Numéro 48, 2024, ISSN 0968-0004
Éditeur: Elsevier BV
DOI: 10.1016/J.TIBS.2023.07.010

Identification of a novel DNA oxidative damage repair pathway, requiring the ubiquitination of the histone variant macroH2A1.1

Auteurs: Khalid Ouararhni, Flore Mietton, Jamal S. M. Sabir, Abdulkhaleg Ibrahim, Annie Molla, Raed S. Albheyri, Ali T. Zari, Ahmed Bahieldin, Hervé Menoni, Christian Bronner, Stefan Dimitrov, Ali Hamiche
Publié dans: BMC Biology, Numéro 22, 2024, ISSN 1741-7007
Éditeur: Springer Science and Business Media LLC
DOI: 10.1186/S12915-024-01987-X