Project description
Transport systems in the context of epidemics and cardiovascular flow
From the transport of blood via different arteries to the movement of people between countries, transport systems are essential. The outbreak of COVID-19 highlighted the importance of efficient and safe biological transport systems. With this in mind, the C-NORA project, funded by the European Research Council, will focus on transport systems in the context of epidemics and cardiovascular flow. The interconnected nature of transport systems makes it challenging to develop effective control design and analysis methodologies. In response, the project will introduce a pioneering holistic framework that accounts for all essential dynamic phenomena and compensates for limited control authority in design. Its scientific gain lies in the introduction of interdisciplinary concepts and ground-breaking control and analysis methodologies.
Objective
"Although ""transport"" may imply different notions for different scientific fields, the feature of incorporation of interacting system components through which ""information'' is propagated remains invariant. Biological transport systems is an example whose significance has become evident with the recent outbreak of COVID-19 spreading. Blood transport in cardiovascular systems falls also under this category. The urgent need of design of efficient/safe, epidemics spreading suppression and congested blood transport monitoring, strategies is apparent, considering the potential, significant socioeconomic impact. However, the continuum, spatiotemporally-varying nature of such interconnected systems, in addition to dynamic complexity and limited available control authority, hamper development of systematic feedback control design and analysis methodologies. C-NORA aims at introduction of a pioneering holistic framework for systematic, computationally tractable control design and analysis of large-scale, interacting, distributed parameter transport systems, which i) harmonizes control at micro-macro levels, ii) accounts in design for all essential dynamic phenomena, iii) compensates adverse effects of limited control authority in design, and iv) develops ad hoc tools for system-specific analysis. C-NORA new control design and analysis tools will be demonstrated in distributed parameter, epidemiological/cardiovascular transport systems and will be validated in numerical simulation. C-NORA high risk lies in unification and complexity of heterogenous, unexplored infinite-dimensional systems, whose treatment requires rethinking of fundamental control-theoretic tools. C-NORA high scientific gain lies in that, on the way of executing its key ideas, novel, interdisciplinary concepts and groundbreaking control/analysis methodologies will be introduced, while unprecedented research arenas will open for systems and control, transport, mathematicians, and systems biologists.
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Fields of science
Programme(s)
- HORIZON.1.1 - European Research Council (ERC) Main Programme
Funding Scheme
HORIZON-ERC - HORIZON ERC GrantsHost institution
731 00 Chania
Greece