Targeting long non-coding RNAs for novel treatment strategies in vascular diseases

Project Information

LongTx

Grant agreement ID: 101088370

DOI

10.3030/101088370

EC signature date 4 May 2023

Start date 1 September 2023

End date 31 August 2028

Funded under

• European Research Council (ERC)

Total cost

€ 1 999 495,00

EU contribution

€ 1 999 495,00

Coordinated by

KLINIKUM DER TECHNISCHEN UNIVERSITÄT MÜNCHEN (TUM KLINIKUM)
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Noncoding RNAs in the Vasculature: Basic Mechanisms and Therapeutic Perspectives

Author(s): Lars Maegdefessel, Reinier A. Boon, Stefanie Dimmeler
Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, Issue 44, 2025, ISSN 1079-5642
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1161/ATVBAHA.123.319564

Long Non-Coding RNA Function in Smooth Muscle Cell Plasticity and Atherosclerosis

Author(s): Lars Maegdefessel, Francesca Fasolo
Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, Issue 45, 2025, ISSN 1079-5642
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1161/ATVBAHA.124.320393

Targeting non-coding RNAs for novel treatment strategies in vascular diseases

Author(s): Hanna Winter, Lars Maegdefessel
Published in: European Heart Journal, Issue 44, 2023, ISSN 0195-668X
Publisher: Oxford University Press (OUP)
DOI: 10.1093/EURHEARTJ/EHAD240

Targeting long non-coding RNA NUDT6 enhances smooth muscle cell survival and limits vascular disease progression

Author(s): Hanna Winter, Greg Winski, Albert Busch, Ekaterina Chernogubova, Francesca Fasolo, Zhiyuan Wu, Alexandra Bäcklund, Bohdan B. Khomtchouk, Derek J. Van Booven, Nadja Sachs, Hans-Henning Eckstein, Ilka Wittig, Reinier A. Boon, Hong Jin, Lars Maegdefessel
Published in: Molecular Therapy, Issue 31, 2025, ISSN 1525-0016
Publisher: Elsevier BV
DOI: 10.1016/J.YMTHE.2023.04.020

Apolipoprotein E (ApoE) Rescues the Contractile Smooth Muscle Cell Phenotype in Popliteal Artery Aneurysm Disease

Author(s): Jessica Pauli, Tessa Reisenauer, Greg Winski, Nadja Sachs, Ekaterina Chernogubova, Hannah Freytag, Christoph Otto, Christian Reeps, Hans-Henning Eckstein, Claus-Jürgen Scholz, Lars Maegdefessel, Albert Busch
Published in: Biomolecules, Issue 13, 2025, ISSN 2218-273X
Publisher: MDPI AG
DOI: 10.3390/BIOM13071074

Integrated single-cell atlas of human atherosclerotic plaques

Author(s): Korbinian Traeuble, Matthias Munz, Jessica Pauli, Nadja Sachs, Eshan Vafadarnejad, Tania Carrillo-Roa, Lars Maegdefessel, Peter Kastner, Matthias Heinig
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-63202-X

Utilization of an Artery‐on‐a‐Chip to Unravel Novel Regulators and Therapeutic Targets in Vascular Diseases

Author(s): Valentina Paloschi, Jessica Pauli, Greg Winski, Zhiyuan Wu, Zhaolong Li, Lorenzo Botti, Sandro Meucci, Pierangelo Conti, Felix Rogowitz, Nadiya Glukha, Nora Hummel, Albert Busch, Ekaterina Chernogubova, Hong Jin, Nadja Sachs, Hans‐Henning Eckstein, Anne Dueck, Reinier A. Boon, Andreas R. Bausch, Lars Maegdefessel
Published in: Advanced Healthcare Materials, Issue 13, 2025, ISSN 2192-2640
Publisher: Wiley
DOI: 10.1002/ADHM.202302907