Regulation of DNA replication origins during normal development and tumorigenesis

Project Information

HS_MSCA_2021

Grant agreement ID: 101090292

DOI

10.3030/101090292

EC signature date 7 December 2022

Start date 1 January 2023

End date 31 December 2026

Funded under

• Widening participation and spreading excellence

Total cost

No data

EU contribution

€ 166 278,72

Coordinated by

BIOFYZIKALNI USTAV AKADEMIE VED CESKE REPUBLIKY
Czechia

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

"#1. Data Management Plan"

The Data Management Plan describes the data management life cycle for all data sets that will be collected, processed or generated by the action. It is a document describing what data will be collected, processed or generated and following what methodology and standards, whether and how this data will be shared and/or made open, and how it will be curated and preserved.

Documents, reports (1)

"#3. Communication, Dissemination & Outreach Plan"

The plan describes the planned measures to maximize the impact of the project, including the dissemination and exploitation measures that are planned, and the target group(s) addressed. Regarding communication measures and public engagement strategy, the aim is to inform and reach out to society and show the activities performed, and the use and the benefits the project will have for citizens.

Publications

Peer reviewed articles (6)

CRL4DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication

Author(s): Anoop Kumar Yadav, Alikhan Abdirov, Katarina Ondruskova, Simran Negi, Kristina Jamrichova, Karolina Kolarova, Nikol Dibus, Jana Krejci, Hana Polasek-Sedlackova, Lukas Cermak
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-64258-5

Returning home: there and back again in Czechia

Author(s): Hana Polasek-Sedlackova
Published in: Nature Structural & Molecular Biology, Issue 32, 2025, ISSN 1545-9993
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41594-025-01642-1

Quantity and quality of minichromosome maintenance protein complexes couple replication licensing to genome integrity

Author(s): Yadav, A.K., Polasek-Sedlackova, H.
Published in: Communications Biology, Issue 7, 2024, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-024-05855-w

RECQ4-MUS81 interaction contributes to telomere maintenance with implications to Rothmund-Thomson syndrome

Author(s): Raghib Ashraf, Hana Polasek-Sedlackova, Victoria Marini, Jana Prochazkova, Zdenka Hasanova, Magdalena Zacpalova, Michala Boudova, Lumir Krejci
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41467-025-56518-1

A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells

Author(s): Anoop Kumar Yadav, Abhijeet S. Jadhav, Pawel M. Szczepanik, Paolo Fagherazzi, Ivo Kabelka, Robert Vácha, Jakub Svenda, Hana Polasek-Sedlackova
Published in: Journal of Cell Biology, Issue 224, 2025, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/JCB.202410025

Cell scientist to watch – Hana Polasek-Sedlackova

Published in: Journal of Cell Science, Issue 138, 2025, ISSN 0021-9533
Publisher: The Company of Biologists
DOI: 10.1242/JCS.264003