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Impact of microplastics originating from formula preparation on protein digestion in infant digestion models

Project description

Study of microplastics impact using protein digestion models

Microplastics (MPs) of various morphologies and sizes have been detected in the environment, posing a threat to food safety and human health. The highest reported MP concentration is found in foods processed in plastic packaging. MP exposure is more prevalent in infants due to the use of polypropylene-based products in formula preparation. The goal of the EU-funded Microprot project is to investigate the effect of MPs originating from plastic packaging on protein digestion in adults and infants. The specific objectives include a comparison of cow’s milk protein digestion in the presence of MPs in adult and infant digestion models and a digestion study of infant formulas in the presence of MPs in infant digestion models.

Objective

Microplastics (MPs) of various morphologies ranging from 1 m - 5.0 mm in size have been ubiquitously detected in the environment, food, drinking water, and biota and may pose a threat to food safety, and human health. The highest reported concentration of MPs comes from the processing of foods in plastic packaging. MPs exposure to humans is more prevalent in infants than in any other age group due to the use of polypropylene (PP) based products in formula preparation. The difference in food intake and digestive physiology between infants and adults have been indicated as key contributors to the distinct patterns of proteolysis. In spite of MPs being frequently consumed with food proteins, data on the digestion process of cows milk in the presence of MPs are not available. The broad aim of the proposal is to investigate the effect of MPs from plastic packaging material on the digestibility of proteins in adults and infants. The project will focus on specific objectives: comparative digestibility of cows milk proteins in the presence of MPs (and aged MPs) in adult and infant digestion models; digestion of infant formulas in the presence of MPs in infant digestion models.
The proposed study will use methodology applied in prior research and harmonised protocols for adult and infant digestion. To achieve the proposed aims, the researcher will get training through know-how transfer and research in digestion models, protein analysis, and digestomics from the University of Belgrade, Faculty of Chemistry and get knowledge on MPs preparation and characterization during the short visit to Maastricht University Polymer Department. The proposed project aims to study an issue that has attracted global attention and therefore, the communication and dissemination measures will be oriented both to the scientific society and the wider public. The project will generate new knowledge on the impact of MPs on human nutrition and provide data that may be adopted by policymakers.

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Topic(s)

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Funding Scheme

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

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(opens in new window) HORIZON-WIDERA-2022-TALENTS-02

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Coordinator

HEMIJSKI FAKULTET, UNIVERZITET U BEOGRADU
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 140 187,84
Address
STUDENTSKI TRG 12-16
11001 Beograd
Serbia

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Region
Србија - север Београдски регион Београдска област
Activity type
Higher or Secondary Education Establishments
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Total cost

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