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Platform Optimisation To Enable NanomaTerIAL safety assessment for rapid commercialisation

Objective

Advanced Nanomaterials (Ad-NMs) will lead a new industrial revolution and accelerate the transition to greener technologies and better health care. However, lack of practical and reliable protocols to evaluate Ad-NMs' potential hazards and risks has hindered innovation so far.
POTENTIAL will generate a methodological framework comprising a set of harmonised protocols for characterisation, testing, grouping and read-across of Ad-NMs, that meet regulatory requirements for risk assessment, by improving:
a) Advanced imaging protocols to quantify and characterize the intrinsic and extrinsic properties of Ad-NMs in complex matrices, using conventional analytical methods.
b) Protocols to trace the evolution of Ad-NMs properties throughout their lifecycle, and methodologies for accelerated testing.
c) in vitro multi-cellular models, in vivo (invertebrate) models, and ecotoxicological models for assessing the environmental and health hazard of Ad-NMs.
Grouping and read-across approaches will build up on results from existing Horizon initiatives (GRACIOUS, SUNSHINE and HARMLESS), and will generate novel algorithms for similarity assessment, grouping hypotheses and Integrated Approaches to Testing and Assessments (IATAs).
The protocols generated in the project will be validated through peer-reviewed publications and disseminated in Open Access. Furthermore, we will engage with the relevant standardisation bodies and organisations (OECD, ISO, CEN) to ensure that our approach can be translated into industry standards.
The consortium comprises 11 European partners and 1 international partner (China), among which 4 high-tech SMEs specialised in Ad-NMs, and a high-tech incubator / accelerator. POTENTIAL contributes to the Horizon Europe workprogram by helping establish appropriate methods for cost-efficient assessment and prediction of the health and environmental effects of Ad-NMs, as well as supporting the inclusion of new methods to support safe-and-sustainable-by-design.

Coordinator

ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
Net EU contribution
€ 677 375,00
Address
Via Mario Negri 2
20156 Milano
Italy

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Region
Nord-Ovest Lombardia Milano
Activity type
Research Organisations
Other funding
€ 0,00

Participants (10)

ROYAL COLLEGE OF SURGEONS IN IRELAND
Ireland
Net EU contribution
€ 338 712,50
Address
St Stephen's Green 123
2 Dublin

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Region
Ireland Northern and Western Border
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
INNOVA SRL
Italy
Net EU contribution
€ 193 537,50
Address
Via Giacomo Peroni 386
00131 Roma

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Centro (IT) Lazio Roma
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY
Luxembourg
Net EU contribution
€ 338 637,50
Address
5 Avenue Des Hauts Fourneaux
4362 Esch Sur Alzette

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Region
Luxembourg Luxembourg Luxembourg
Activity type
Research Organisations
Other funding
€ 0,00
ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE
Spain
Net EU contribution
€ 338 687,50
Address
Paseo Miramon 182, Parque Tecnologico De San Sebastian Edificio Empresarial C
20009 San Sebastian

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Region
Noreste País Vasco Gipuzkoa
Activity type
Research Organisations
Other funding
€ 0,00
EAST EUROPEAN RESEARCH AND INNOVATION ENTERPRISE LTD
Bulgaria
Net EU contribution
€ 193 537,50
Address
Mladost 2, 280a, Entr. 3, Floor 4, Ap. 19
1799 Sofia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Югозападна и Южна централна България Югозападен София (столица)
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
MYBIOTECH GMBH
Germany
Net EU contribution
€ 193 550,00
Address
Industriestrasse 1b
66802 Uberherrn

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Saarland Saarland Saarlouis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
GREENDECISION SRL
Italy
Net EU contribution
€ 193 537,50
Address
Via Torino 155/a
30172 Venezia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Est Veneto Venezia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
GRAPHENEA SA
Spain
Net EU contribution
€ 145 162,50
Address
Paseo Mikeletegi 83
20009 San Sebastian Guipuzcoa

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Noreste País Vasco Gipuzkoa
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSITAET LEIPZIG
Germany
Net EU contribution
€ 241 900,00
Address
Ritterstrasse 26
04109 Leipzig

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Region
Sachsen Leipzig Leipzig
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERSITE PARIS 13
France
Net EU contribution
€ 145 150,00
Address
Avenue Jean-baptiste Clement 99
93430 Villetaneuse

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Region
Ile-de-France Ile-de-France Seine-Saint-Denis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Partners (1)

Zhejiang University
China
Net EU contribution
€ 0,00
Address
Zhe Da Road 38
310027 Hangzhou

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00