TARGETING INHERITED CANCER SYNDROMES

Project Information

INCANTAR

Grant agreement ID: 101097752

DOI

10.3030/101097752

EC signature date 12 June 2023

Start date 1 September 2023

End date 31 August 2028

Funded under

• European Research Council (ERC)

Total cost

€ 2 496 625,00

EU contribution

€ 2 496 625,00

Coordinated by

FONDAZIONE TELETHON ETS
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

ATG conjugation–dependent/independent mechanisms underlie lysosomal stress–induced TFEB regulation

Author(s): Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura
Published in: Journal of Cell Biology, Issue 224, 2025, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/JCB.202307079

Structural basis for mTORC1 activation on the lysosomal membrane

Author(s): Zhicheng Cui, Alessandra Esposito, Gennaro Napolitano, Andrea Ballabio, James H. Hurley
Published in: Nature, 2025, ISSN 0028-0836
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41586-025-09545-3

Age-related TFEB downregulation in proximal tubules causes systemic metabolic disorders and occasional apolipoprotein A4–related amyloidosis

Author(s): Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Hiroaki Yonishi, Shihomi Maeda, Sho Matsui, Hideaki Kawai, Isao Matsui, Tadashi Yamamuro, Ryuya Edahiro, Seiji Takashima, Akira Takasawa, Yukinori Okada, Tamotsu Yoshimori, Andrea Ballabio, Yoshitaka Isaka
Published in: JCI Insight, Issue 10, 2025, ISSN 2379-3708
Publisher: American Society for Clinical Investigation
DOI: 10.1172/JCI.INSIGHT.184451

Folliculin depletion results in liver cell damage and cholangiocarcinoma through MiT/TFE activation

Author(s): Bruno Maria Custode, Francesco Annunziata, Felipe Dos Santos Matos, Valentina Schiano, Veronica Maffia, Milena Lillo, Rita Colonna, Rossella De Cegli, Andrea Ballabio, Nunzia Pastore
Published in: Cell Death & Differentiation, Issue 32, 2025, ISSN 1350-9047
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41418-025-01486-8

Other (1)

Structural basis for growth factor and nutrient signal integration on the lysosomal membrane by mTORC1

Author(s): Zhicheng Cui; Alessandra Esposito; Gennaro Napolitano; Andrea Ballabio; James H. Hurley
Published in: bioRxiv, 2024
Publisher: bioRxiv
DOI: 10.1101/2024.11.15.623810