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The ANAEROBic treasure trunk

Project description

Novel platform supports the creation of tailor-made anaerobic microbial communities

Technologies using microbes for valorisation of organic waste and industrial or agricultural residual materials have progressed significantly. Since it is difficult to operate with pure cultures when wastes are the feedstock, it is important to use robust mixed cultures which result in high yields without the need of sterile conditions. It is well recognised that anaerobic microbes have very diverse metabolic pathways. Full exploitation of these to achieve upcycling of waste and production of materials, biochemicals, and energy in a circular economy will require establishing tailor-made microbial communities. The ERC-funded ANAEROB project aims to develop a platform supporting the creation of application-specific microbial consortia based on the genetic information of anaerobic microorganisms.

Objective

ANAEROB aims to generate a platform that enables linking of microbial ecology to biotechnology. This platform should be general and applicable to a very wide range of conditions and applications. Anaerobic processes are performed by a well-structured microbial community and have a great potential for upcycling organic wastes and industrial/agricultural residual resources to achieve circular bioeconomy. Upcycling of residual resources through production of materials, biochemicals and energy is a promising way towards a more sustainable production. Pure culture fermentations are not appropriate when wastes are the substrate and therefore mixed culture microbial consortia are required. Currently inocula for biological processes utilizing wastes as substrates are random self-established cultures. Comprehensive knowledge about the microbial interactions of the anaerobic microbiome is needed for valorization and remediation of biowastes. The overall aim of ANAEROB is to understand how to create designer microbial consortia for specific bioengineering processes based on genetic information of anaerobic microorganisms. The aim will be achieved by: 1. Elucidating the syntrophic mutualistic symbioses of the anaerobic microbiome, and clarifying the role of specific compounds exchanged by microbes; 2. Developing models for prediction of desired pathways; 3. Developing methods for isolation of new unculturable anaerobes; 4. Developing a novel method for designing and establishing microbial cocktails for specific functions and 5. Validating the concept of creating specific anaerobic consortia for upcycling gas streams of carbon-intensive industries. ANAEROB takes a multidisciplinary approach to use both engineering and microbiology to reach at the next level of understanding for exploitation of the anaerobic microbial treasure. The projects successful completion will have major benefits in industrial sectors and environmental applications.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-ERC - HORIZON ERC Grants

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Call for proposal

(opens in new window) ERC-2022-ADG

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Host institution

DANMARKS TEKNISKE UNIVERSITET
Net EU contribution
€ 2 494 159,00
Address
ANKER ENGELUNDS VEJ 101
2800 Kongens Lyngby
Denmark
Region
Danmark Hovedstaden Københavns omegn
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 2 494 159,00

Beneficiaries (1)