Dissecting the cancer epigenome – fundamental lessons from developmental biology

Project Information

CancerEpigenome

Grant agreement ID: 101098178

DOI

10.3030/101098178

EC signature date 3 August 2023

Start date 1 January 2024

End date 31 December 2028

Funded under

• European Research Council (ERC)

Total cost

€ 2 487 500,00

EU contribution

€ 2 487 500,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

Non-disruptive in vitro monitoring of cellular states with cell-free DNA methylation

Author(s): Anja Hess, Alexander Kovacsovics, Fabian Bachinger, Ludovic Vallier, Helene Kretzmer, Alexander Meissner
Published in: Genome Biology, Issue 27, 2026, ISSN 1474-760X
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S13059-026-03996-1

Extraembryonic gut endoderm cells undergo programmed cell death during development

Author(s): Julia Batki, Sara Hetzel, Dennis Schifferl, Adriano Bolondi, Maria Walther, Lars Wittler, Stefanie Grosswendt, Bernhard G. Herrmann, Alexander Meissner
Published in: Nature Cell Biology, Issue 26, 2024, ISSN 1465-7392
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41556-024-01431-W

Direct genetic transformation bypasses tumor-associated DNA methylation alterations

Author(s): Sara Hetzel, Eran Hodis, Elena Torlai Triglia, Alexander Kovacsovics, Kathleen Steinmann, Andreas Gnirke, Meiying Cui, Daniel McQuaid, Raha Weigert, Georg Pohl, Mandar D. Muzumdar, Serge Leyvraz, Ulrich Keilholz, Marie-Laure Yaspo, Aviv Regev, Helene Kretzmer, Zachary D. Smith, Alexander Meissner
Published in: Genome Biology, Issue 26, 2025, ISSN 1474-760X
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S13059-025-03650-2