Piezo-driven theramesh: A revolutionary multifaceted actuator to repair the injured spinal cord

Project Information

Piezo4Spine

Grant agreement ID: 101098597

DOI

10.3030/101098597

EC signature date 15 December 2022

Start date 1 January 2023

End date 31 December 2026

Funded under

• The European Innovation Council (EIC)

Total cost

€ 3 537 121,25

EU contribution

€ 3 537 120,25

Coordinated by

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (5)

Web site and project logo

Website and project logo information with also social media links

3D-theramesh performance 1

Public Report on in-vitro biocompatibility and biodegradability of the 3D-theramesh developed

Therapeutic release in vitro

Public Report on the on-demand release from the active integrated device in vitro

3D-theramesh performance 2

Public Report on the in-vitro functional performance of the 3D-theramesh developed

In-vitro actuation

Public Report on the demonstration of the nanomechanical actuation principle in cells by AFM

Publications

Peer reviewed articles (14)

An organic artificial soma for spatio-temporal pattern recognition via dendritic integration

Author(s): Michele Di Lauro, Federico Rondelli, Anna De Salvo, Alessandro Corsini, Matteo Genitoni, Pierpaolo Greco, Mauro Murgia, Luciano Fadiga, Fabio Biscarini
Published in: Neuromorph. Comput. Eng., Issue 4, 2024, ISSN 1742-6596
Publisher: IOP Publishing
DOI: 10.1088/2634-4386/ad3a96

Electrodeposited Reduced Graphene Oxide Enables Long‐Term Memory in Neuromorphic Ambipolar Electrolyte‐Gated Transistors

Author(s): Maryam Abouali, Federico Rondelli, Matteo Genitoni, Mauro Murgia, Michele Di Lauro, Luciano Fadiga, Fabio Biscarini
Published in: Small, Issue 21, 2025, ISSN 1613-6810
Publisher: Wiley
DOI: 10.1002/SMLL.202502768

Advances in nanomechanical property mapping by atomic force microscopy

Author(s): Ricardo Garcia, Jaime R. Tejedor
Published in: Nanoscale Advances, 2025, ISSN 2516-0230
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5NA00702J

Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats

Author(s): Marta Zaforas, Esther Benayas, Raquel Madroñero-Mariscal, Ana Domínguez-Bajo, Elena Fernández-López, Yasmina Hernández-Martín, Ankor González-Mayorga, Elena Alonso-Calviño, Eduardo R. Hernández, Elisa López-Dolado, Juliana M. Rosa, Juan Aguilar, María C. Serrano
Published in: Bioactive Materials, Issue 47, 2025, ISSN 2452-199X
Publisher: Elsevier BV
DOI: 10.1016/J.BIOACTMAT.2024.12.031

High‐Throughput Nanorheology of Living Cells Powered by Supervised Machine Learning

Author(s): Jaime R. Tejedor, Ricardo Garcia
Published in: Advanced Intelligent Systems, Issue 7, 2025, ISSN 2640-4567
Publisher: Wiley
DOI: 10.1002/AISY.202400867

Evidence of the bottom stiffness effect on atomic force microscopy-based cell mechanobiology

Author(s): Afonso L. D. Moura, Jaime R. Tejedor, Francisco M. Espinosa, Lázaro A. Dominguez, Jeanlex S. de Sousa, Ricardo Garcia
Published in: Nanoscale, Issue 17, 2025, ISSN 2040-3364
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5NR01236H

How Biorecognition Affects the Electronic Properties of Reduced Graphene Oxide in Electrolyte-Gated Transistor Immunosensors

Author(s): Matteo Sensi, Rafael Furlan de Oliveira, Marcello Berto, Alessandro Paradisi, Pierpaolo Greco, Carlo Augusto Bortolotti, Paolo Samorì, Fabio Biscarini
Published in: Advanced Functional Materials, Issue 34, 2024, ISSN 1616-3028
Publisher: Wiley-VCH GmbH
DOI: 10.1002/adfm.202313871

3D nanofibrous frameworks with on-demand engineered gray and white matters for reconstructing the injured spinal cord

Author(s): André F. Girão, Nathalie Barroca, Yasmina Hernández-Martín, António Completo, Paula A.A.P. Marques, María C. Serrano
Published in: Biomaterials Advances, Issue 170, 2025, ISSN 2772-9508
Publisher: Elsevier BV
DOI: 10.1016/J.BIOADV.2025.214200

Nanorheology and Nanoindentation Revealed a Softening and an Increased Viscous Fluidity of Adherent Mammalian Cells upon Increasing the Frequency

Author(s): Victor G. Gisbert, Francsico M. Espinosa, Juan G. Sanchez, Maria Concepcion Serrano, and Ricardo Garcia
Published in: Small, Issue 2304884, 2023, ISSN 1613-6829
Publisher: Wiley-VCH GmbH
DOI: 10.1002/SMLL.202304884

A Single Electrode Organic Neuromorphic Device for Dopamine Sensing in Vivo

Author(s): Federico Rondelli, Michele Di Lauro, Gioacchino Calandra Sebastianella, Anna De Salvo, Matteo Genitoni, Mauro Murgia, Pierpaolo Greco, Carolina Giulia Ferroni, Riccardo Viaro, Luciano Fadiga, Fabio Biscarini
Published in: Advanced Electronic Materials, Issue 10, 2025, ISSN 2199-160X
Publisher: Wiley
DOI: 10.1002/AELM.202400467

Cellular and Molecular Processes Are Differently Influenced in Primary Neural Cells by Slight Changes in the Physicochemical Properties of Multicore Magnetic Nanoparticles

Author(s): Esther Benayas; Ana Espinosa; M. Teresa Portolés; Virginia Vila-del Sol; M. Puerto Morales; and María C. Serrano*
Published in: ACS Applied Materials and Interfaces, Issue 15, 2023, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/ACSAMI.3C02729

Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats

Author(s): Marta Zaforas, Esther Benayas, Raquel Madroñero-Mariscal, Ana Domínguez-Bajo, Elena Fernández-López, Yasmina Hernández-Martín, Ankor González-Mayorga, Elena Alonso-Calviño, Eduardo R. Hernández, Elisa López-Dolado, Juliana M. Rosa, Juan Aguilar, María C. Serrano
Published in: Bioactive Materials, Issue 47, 2025, ISSN 2452-199X
Publisher: Elsevier BV
DOI: 10.1016/j.bioactmat.2024.12.031

Synergy of Nanotopography and Electrical Conductivity of PEDOT/PSS for Enhanced Neuronal Development

Author(s): Michele Bianchi, Sonia Guzzo, Alice Lunghi, Pierpaolo Greco, Alessandra Pisciotta, Mauro Murgia, Gianluca Carnevale, Luciano Fadiga, Fabio Biscarini
Published in: ACS Applied Materials and Interfaces, Issue 15, 2023, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/ACSAMI.3C15278

Hybrid hydrogels support neural cell culture development under magnetic actuation at high frequency

Author(s): Julia Martínez-Ramírez1, Marta Toldos-Torres1, Esther Benayas, Natalia Villar, Laura Fernández-Méndez, Francisco M. Espinosa, Ricardo García, Sabino Veintemillas-Verdaguer, María del Puerto Morales, María Concepción Serrano⁎
Published in: Acta Biomaterialia, Issue 176, 2024, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/J.ACTBIO.2024.01.030