Piezo-driven theramesh: A revolutionary multifaceted actuator to repair the injured spinal cord

Informazioni relative al progetto

Piezo4Spine

ID dell’accordo di sovvenzione: 101098597

DOI

10.3030/101098597

Data della firma CE 15 Dicembre 2022

Data di avvio 1 Gennaio 2023

Data di completamento 31 Dicembre 2026

Finanziato da

• The European Innovation Council (EIC)

Costo totale

€ 3 537 121,25

Contributo UE

€ 3 537 120,25

Coordinato da

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (5)

Web site and project logo

Website and project logo information with also social media links

3D-theramesh performance 1

Public Report on in-vitro biocompatibility and biodegradability of the 3D-theramesh developed

Therapeutic release in vitro

Public Report on the on-demand release from the active integrated device in vitro

3D-theramesh performance 2

Public Report on the in-vitro functional performance of the 3D-theramesh developed

In-vitro actuation

Public Report on the demonstration of the nanomechanical actuation principle in cells by AFM

Pubblicazioni

Peer reviewed articles (14)

An organic artificial soma for spatio-temporal pattern recognition via dendritic integration

Autori: Michele Di Lauro, Federico Rondelli, Anna De Salvo, Alessandro Corsini, Matteo Genitoni, Pierpaolo Greco, Mauro Murgia, Luciano Fadiga, Fabio Biscarini
Pubblicato in: Neuromorph. Comput. Eng., Numero 4, 2024, ISSN 1742-6596
Editore: IOP Publishing
DOI: 10.1088/2634-4386/ad3a96

Electrodeposited Reduced Graphene Oxide Enables Long‐Term Memory in Neuromorphic Ambipolar Electrolyte‐Gated Transistors

Autori: Maryam Abouali, Federico Rondelli, Matteo Genitoni, Mauro Murgia, Michele Di Lauro, Luciano Fadiga, Fabio Biscarini
Pubblicato in: Small, Numero 21, 2025, ISSN 1613-6810
Editore: Wiley
DOI: 10.1002/SMLL.202502768

A regenerative rehabilitation strategy based on rGO scaffolds and treadmill training boosts neural, vascular and muscle repair features in chronic hemisected rats

Autori: Esther Benayas, Raquel Madroñero-Mariscal, Yasmina Hernández-Martín, Jose A. Rodríguez-Alfaro, Javier Mazarío, Francisco M. Espinosa, Ricardo García, José L. Polo, Ankor González-Mayorga, Elisa López-Dolado, María C. Serrano
Pubblicato in: Biomaterials, Numero 333, 2026, ISSN 0142-9612
Editore: Elsevier BV
DOI: 10.1016/J.BIOMATERIALS.2026.124164

Advances in nanomechanical property mapping by atomic force microscopy

Autori: Ricardo Garcia, Jaime R. Tejedor
Pubblicato in: Nanoscale Advances, 2025, ISSN 2516-0230
Editore: Royal Society of Chemistry (RSC)
DOI: 10.5281/ZENODO.17202437

Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats

Autori: Marta Zaforas, Esther Benayas, Raquel Madroñero-Mariscal, Ana Domínguez-Bajo, Elena Fernández-López, Yasmina Hernández-Martín, Ankor González-Mayorga, Elena Alonso-Calviño, Eduardo R. Hernández, Elisa López-Dolado, Juliana M. Rosa, Juan Aguilar, María C. Serrano
Pubblicato in: Bioactive Materials, Numero 47, 2025, ISSN 2452-199X
Editore: Elsevier BV
DOI: 10.1016/J.BIOACTMAT.2024.12.031

High‐Throughput Nanorheology of Living Cells Powered by Supervised Machine Learning

Autori: Jaime R. Tejedor, Ricardo Garcia
Pubblicato in: Advanced Intelligent Systems, Numero 7, 2025, ISSN 2640-4567
Editore: Wiley
DOI: 10.5281/ZENODO.17202339

Evidence of the bottom stiffness effect on atomic force microscopy-based cell mechanobiology

Autori: Afonso L. D. Moura, Jaime R. Tejedor, Francisco M. Espinosa, Lázaro A. Dominguez, Jeanlex S. de Sousa, Ricardo Garcia
Pubblicato in: Nanoscale, Numero 17, 2025, ISSN 2040-3364
Editore: Royal Society of Chemistry (RSC)
DOI: 10.5281/ZENODO.17202383

How Biorecognition Affects the Electronic Properties of Reduced Graphene Oxide in Electrolyte-Gated Transistor Immunosensors

Autori: Matteo Sensi, Rafael Furlan de Oliveira, Marcello Berto, Alessandro Paradisi, Pierpaolo Greco, Carlo Augusto Bortolotti, Paolo Samorì, Fabio Biscarini
Pubblicato in: Advanced Functional Materials, Numero 34, 2024, ISSN 1616-3028
Editore: Wiley-VCH GmbH
DOI: 10.1002/adfm.202313871

Maskless Fabrication of PLA‐Based Neural Arrays for CNS Recording and Stimulation

Autori: Anna De Salvo, Federica Velluto, Ilenia Sergi, Michele Di Lauro, Verónica Barranco‐Maresca, Elena Alonso‐Calviño, Yasmina Hernández‐Martín, Juan Aguilar, Juliana M. Rosa, María C. Serrano, Carolina Giulia Ferroni, Federico Rondelli, Elisa López‐Dolado, Luciano Fadiga, Fabio Biscarini
Pubblicato in: Advanced Materials Interfaces, 2026, ISSN 2196-7350
Editore: Wiley
DOI: 10.1002/ADMI.70601

Nanorheology and Nanoindentation Revealed a Softening and an Increased Viscous Fluidity of Adherent Mammalian Cells upon Increasing the Frequency

Autori: Victor G. Gisbert, Francsico M. Espinosa, Juan G. Sanchez, Maria Concepcion Serrano, and Ricardo Garcia
Pubblicato in: Small, Numero 2304884, 2023, ISSN 1613-6829
Editore: Wiley-VCH GmbH
DOI: 10.1002/SMLL.202304884

A Single Electrode Organic Neuromorphic Device for Dopamine Sensing in Vivo

Autori: Federico Rondelli, Michele Di Lauro, Gioacchino Calandra Sebastianella, Anna De Salvo, Matteo Genitoni, Mauro Murgia, Pierpaolo Greco, Carolina Giulia Ferroni, Riccardo Viaro, Luciano Fadiga, Fabio Biscarini
Pubblicato in: Advanced Electronic Materials, Numero 10, 2025, ISSN 2199-160X
Editore: Wiley
DOI: 10.1002/AELM.202400467

Cellular and Molecular Processes Are Differently Influenced in Primary Neural Cells by Slight Changes in the Physicochemical Properties of Multicore Magnetic Nanoparticles

Autori: Esther Benayas; Ana Espinosa; M. Teresa Portolés; Virginia Vila-del Sol; M. Puerto Morales; and María C. Serrano*
Pubblicato in: ACS Applied Materials and Interfaces, Numero 15, 2023, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/ACSAMI.3C02729

Synergy of Nanotopography and Electrical Conductivity of PEDOT/PSS for Enhanced Neuronal Development

Autori: Michele Bianchi, Sonia Guzzo, Alice Lunghi, Pierpaolo Greco, Alessandra Pisciotta, Mauro Murgia, Gianluca Carnevale, Luciano Fadiga, Fabio Biscarini
Pubblicato in: ACS Applied Materials and Interfaces, Numero 15, 2023, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/ACSAMI.3C15278

Hybrid hydrogels support neural cell culture development under magnetic actuation at high frequency

Autori: Julia Martínez-Ramírez1, Marta Toldos-Torres1, Esther Benayas, Natalia Villar, Laura Fernández-Méndez, Francisco M. Espinosa, Ricardo García, Sabino Veintemillas-Verdaguer, María del Puerto Morales, María Concepción Serrano⁎
Pubblicato in: Acta Biomaterialia, Numero 176, 2024, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/J.ACTBIO.2024.01.030