Project description
More accurate and efficient deep body functional imaging
The visualisation of internal organs and structures, as well as the monitoring of their functions, is important for the diagnosis and treatment of various medical conditions like cancer and cardiovascular disease. Currently, ultrasound, X-rays, positron emission tomography, and MRI are used for monitoring organs and deep body imaging, but they have their limitations. The EU-funded fastMOT project aims to revolutionise the way deep body functional imaging is done. It proposes a light sensing solution, an ultra-fast and highly efficient single-photon sensor based on superconducting nanowire detectors. By combining optical gating and charge coupling, it will scale up to 10 000 pixels and millimetre diameter to enable multifunctional deep body imaging with diffuse optics.
Objective
Traditionally, monitoring of organs and deep body functional imaging is done by ultrasound, X-Rays (incl. CT), PET or MRI. These techniques only allow for very limited measurements of functionality, usually combined with exogenous and radioactive agents. In this project we propose an innovative light sensing solution, an ultra-high quantum efficiency single-photon sensor, to enable multi-functional deep body imaging with diffuse optics. The new type of sensor is based on superconducting nanowire single-photon detectors, that have shown to be ultra-fast and highly efficient. However, until now the active area and number of pixels have been limited to micrometer-scale active areas and tens of pixels. We propose to expand the capabilities of SNSPD technology at a system level by developing a scalable multi-pixel architecture with individually addressed detectors and full time-tagging capabilities, enabling larger active areas and richer time-resolved information. In addition, we will develop new strategies for performing TD-NIRS and TD-SCOS to use this new light sensor optimally with Monte-Carlo simulations. We will implement the new light sensor in an optical tomograph and achieve a >10× improvement in SNR compared to existing light sensing solutions, while providing access to the full photon time-of-flight distribution. With our proposed Multifunctional Optical Tomograph, we will be able to image deep organ and optical structures and monitor functions including oxygenation, haemodynamics, perfusion and metabolism.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- natural sciences physical sciences theoretical physics particle physics photons
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2022-PATHFINDEROPEN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2628 ER Delft
Netherlands
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.