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Novel and sustainable biotechnological approaches for astaxanthin and ketocarotenoids production

Project description

Engineered microalgae to produce bio-based products

Astaxanthin is a natural carotenoid pigment found in sea microalgae, salmon, and trout. It is believed to have antioxidant and antihypertension properties but is mainly used in animal feed for pigmentation. Currently, astaxanthin is mainly generated by chemical synthesis as the cost for its extraction and production from natural sources is high. Funded by the European Innovation Council, the ASTEASIER project aims to develop novel methods to produce and extract astaxanthin from microalgae. The idea is to establish a sustainable industrial platform based on engineered microalgae for producing high-value bio-based products such as astaxanthin and omega-3 for human and animal nutrition.

Objective

Microalgae are photosynthetic unicellular microorganisms which can be cultivated at industrial level and adopted as sustainable platforms to produce high value biobased products. Astaxanthin and omega-3 fatty acids are examples of high value metabolites which can be produced by microalgae and that are relevant for both human and animal nutrition. Astaxanthin is widely used in animal feed for its pigmentation properties, but it’s also used in nutraceutics, being among the strongest antioxidants found in nature. Despite the high potential of microalgae, nowadays astaxanthin is mainly derived from chemical synthesis, due to the high costs for natural astaxanthin production and extraction, with selling price in the market reaching several thousands of €/kg. However, synthetic astaxanthin has a far less antioxidant power compared to natural one and its production processes present several sustainability issues.

The ASTEASIER project starts from the results of ERC PoC project Asteasy, where novel biotechnological solutions to efficiently produce natural astaxanthin were developed, reducing the production costs compared to the state-of-the-art processes. Moreover, the ASTEASIER solution allows an easy extraction of astaxanthin in a wide range of bland solvents, and the simultaneous production of both astaxanthin and omega-3, required for fish feed formulation, were developed. Here these innovations will be validated in demonstrator units and tested for aquaculture feed formulation. ASTEASIER proposal is thus focused on the development and validation of these novel methods to produce and extract astaxanthin from microalgae and aims, in line with the EIC Transition work Pogramme, to take the technologies to TRL6 and to spin-off a company who will become leader in engineering microalgae to produce and sell natural products such as astaxanthin for human and animal nutrition and wellness

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Coordinator

UNIVERSITA DEGLI STUDI DI VERONA
Net EU contribution
€ 619 934,00
Address
VIA DELL ARTIGLIERE 8
37129 Verona
Italy

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Region
Nord-Est Veneto Verona
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 619 934,00

Participants (3)