Transcription Factor Gene Therapy for Bradyarrhythmias

Project Information

TRACTION

Grant agreement ID: 101099608

DOI

10.3030/101099608

Project closed

EC signature date 21 November 2022

Start date 1 January 2023

End date 31 December 2025

Funded under

• The European Innovation Council (EIC)

Total cost

€ 2 499 968,75

EU contribution

€ 2 499 968,00

Coordinated by

PACINGCURE B.V.
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (2)

<i>SCN10A-short</i> gene therapy to restore conduction and protect against malignant cardiac arrhythmias

Author(s): Jianan Wang; Arie O Verkerk; Ronald Wilders; Yingnan Zhang; Kelly Zhang; Adityo Prakosa; Mathilde R Rivaud; E Madelief J Marsman; Arie R Boender; Mischa Klerk; Lianne Fokkert; Berend de Jonge; Klaus Neef; Osne F Kirzner; Connie R Bezzina; Carol Ann Remme; Hanno L Tan; Bastiaan J Boukens; Harsha D Devalla; Natalia A Trayanova; Vincent M Christoffels; Phil Barnett; Gerard J J Boink
Published in: European Heart Journal, 2025, ISSN 1522-9645
Publisher: Oxford Academic
DOI: 10.1093/EURHEARTJ/EHAF053

AAV6 vectors provide superior gene transfer compared to AAV9 vectors following intramyocardial administration

Author(s): Jianan Wang; Timo Jonker; Aina Cervera-Barea; Zhenyu Dong; Ruud N. Visser; Evelien E. Birza; Arie R. Boender; Mischa Klerk; Yuting Yang; Joyce Visser; Marlijn S. Jansen; Tom C. Grootswagers; Cindy I. Bart; Saskia C.A. de Jager; Silke Schrödel; Christian Thirion; Osne F. Kirzner; Hanno L. Tan; Antoine A.F. de Vries; Joost P.G. Sluijter; Klaus Neef; Joris R. de Groot; Vincent M. Christoffels; Gerard J.J. Boink
Published in: Molecular Therapy Methods &amp; Clinical Development, 2025, ISSN 2329-0501
Publisher: Cell Press / Elsevier
DOI: 10.1016/J.OMTM.2025.101532