INTERMITTENT ANDROGEN DEPRIVATION THERAPY IN THE ERA OF ANDROGEN RECEPTOR PATHWAY INHIBITORS; A PHASE 3 PRAGMATIC RANDOMISED TRIAL

Project Information

DE-ESCALATE

Grant agreement ID: 101104574

DOI

10.3030/101104574

EC signature date 21 April 2023

Start date 1 June 2023

End date 31 May 2028

Funded under

• Health

Total cost

€ 7 185 663,75

EU contribution

€ 7 185 663,00

Coordinated by

EUROPEAN ORGANISATION FOR RESEARCH AND TREATMENT OF CANCER AISBL
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (7)

Conclusions of common annual meeting of the ‘Diagnosis and treatment’ cluster 2

Conclusions of common annual meeting of the ‘Diagnosis and treatment’ cluster

Plan for dissemination and exploitation

The plan that will describe project strategy for communication and dissemination

Conclusions of common annual meeting of the ‘Diagnosis and treatment’ cluster 1

Conclusions of common annual meeting of the ‘Diagnosis and treatment’ cluster

Policy brief 1

Policy brief formulating recommendations based on the research and innovation strand of the ‘Diagnosis and treatment’ annual cluster meeting

Data Management Plan

The DMP will describe which data/variables are collected, the standards used, how they are processed and stored and how they could be accessed.The preparation of the Data Management Plan will include a common chapter on the ‘Diagnosis and treatment’ cluster. The aim is of the chapter is to address commonalities in data standards, data validation, data protection and foster data exchange.

Policy brief 2

Policy brief formulating recommendations based on the research and innovation strand of the ‘Diagnosis and treatment’ annual cluster meeting

Initial common work plan for scientific collaboration under the ‘Diagnosis and treatment’ cluster

Other (2)

Common video and/or a common cluster brochure and associated Deliverable

common video and/or a common cluster brochure and associated Deliverable

Project website is online

launch of the project dedicated public website

Publications

Peer reviewed articles (2)

Systematic Literature Review on Economic Evaluations and Health Economic Models in Metastatic Castration-Sensitive Prostate Cancer

Author(s): Thanh Tu Nguyen; David Ameyaw; George Dennis Obeng; Rose Amuah; Judit Józwiak-Hagymásy; Tamás Dóczi; Dóra Mezei; Bertalan Németh; Attila Tordai; Ahu Alanya; Guillaume Grisay; Marcell Csanádi
Published in: Current Oncology, 2025, ISSN 1718-7729
Publisher: MDPI AG
DOI: 10.3390/CURRONCOL32080412

"EORTC 2238 ""De-Escalate"": a pragmatic trial to revisit intermittent androgen deprivation therapy in the era of new androgen receptor pathway inhibitors."

Author(s): Grisay G, Turco F, Litiere S, Fournier B, Patrikidou A, Gallardo E, McDermott R, Alanya A, Gillessen S, Tombal B
Published in: Frontiers in oncology, 2024, ISSN 1664-3224
Publisher: Frontiers media
DOI: 10.3389/FONC.2024.1391825

Conference proceedings (1)

EORTC GUCG 2238 De-escalate: A pragmatic trial to revisit intermittent androgen-deprivation therapy in metastatic hormone-naïve prostate cancer in the era of new AR pathway inhibitors.

Author(s): Guillaume Grisay, Fabio Turco, Anna Patrikidou, Enrique Gallardo Díaz, Raymond S. McDermott, Saskia Litiere, Beatrice Fournier, Silke Gillessen, and Bertrand F. Tombal
Published in: Journal of Clinical Oncology, 2024, ISSN 0732-183X
Publisher: American Society of Clinical Oncology
DOI: 10.1200/JCO.2024.42.4_suppl.TPS2