Human skeletal remains can offer key information on diverse aspects of past life but, like all archaeological materials, they only give a glimpse into the life of past individuals; hence, a fragmented perspective into our ancestors’ lives. Their interpretative potential is greatly inhibited by the fact that such remains are often found fragmented due to several anthropogenic and natural taphonomic agents, such as funerary treatment, animal activity, soil pressure and others. This fragmentation severely limits the information that may be extracted from human bones in terms of metric analysis, geometry and morphology. RECONSTRUCT aimed at producing 3D morphable models for the main elements of the lower and upper limbs of the human skeleton, which would be then used to infer the missing morphology of fragmented or incomplete bones. In order to achieve this aim and address a major current limitation in human skeletal analysis, RECONSTRUCT integrated approaches from osteoarchaeology, forensic anthropology, biology, engineering, and data science. The results of the project can indeed maximize the information that may be extracted from bioarchaeological research, contributing to a more comprehensive assessment of past life parameters. RECONSTRUCT also has major implications in forensic anthropology since the study of modern skeletal remains suffers from similar limitations in terms of partial preservation as those witnessed in archaeological bones. Finally, the source code and raw data emanating from RECONSTRUCT have been made open access, making the approach easily transferable to zooarchaeology, palaeoanthropology, and other fields.