Objective
The increasing level of carbon dioxide (CO2) in the atmosphere presents a critical factor for climate change and action must be taken urgently to minimise its impact. Using CO2 as a carbon source in the chemical industry for its conversion into valuable chemicals is an advantageous strategy to reduce CO2 emissions and provide a sustainable and cheap source of raw materials to help combat raw material scarcity. Interfacing CO2 reducing enzyme/enzymatic cascades with electrocatalysis present a particular approach to directly power product generation from CO2 with renewable electricity. This was achieved for a few enzymatic cascades; however, these proof-of-concept demonstrations are far from practical use due to lack of efficient method to guide the rational design of these complex multi-enzymes cascades on electrodes, resulting in high costs and low yields. Within this project (TransCO2), my overarching aim is to apply quantitative analysis and rational assembly of enzymatic cascades to enable a breakthrough in bioelectrocatalytic-technology to transform carbon dioxide (CO2) directly into high value mevalonate (C5) at high isolated yields, using electricity as energy source. Specifically, CO2 is firstly converted to formate by the enzyme Formate dehydrogenase (FDH), which is then further converted to mevalonate via 8 steps enzymatic conversions. The whole system will function in an electrochemical cell to make use of electricity as power input. I will build a kinetic model for this enzymatic cascade and implement it to guide the design and optimisation towards highest efficiency with minimal utilization of expensive cofactors.The overall technology in TransCO2 will be a generally applicable breakthrough for efficient production of high-value chemicals from CO2, enabling the large-scale use of CO2 utilisation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences catalysis electrocatalysis
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
80333 Muenchen
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.