Objective
The human gut microbiome is recognized as an essential element in human health and disruption of the homeostasis between the host and gut microbiome has been associated with the development of various diseases. Diet plays a major role in modulating the gut microbiome, but understanding the exact relationship and its effect on health remains a key challenge in microbiome research. NUTROME aims to develop nutraceuticals (food components with health benefits) based on key dietary components of the Mediterranean diet that are capable of modulating imbalances (or dysbiosis) on the human gut microbiome of two relevant population groups (the elderly, and people with irritable bowel syndrome). Understanding how key dietary components and gut microbiome interact in the context of dysbiosis will require insight of the taxonomic and functional composition and relevant ecological dynamics of the microbiome by cutting-edge microbiome manipulations and multi-omics approach. Joint analyses of metagenomics, metabolomics and metaproteomics data, together with measures of mechanistic experiments in in vitro (cells) and an in vivo (germ-free mice) model will allow me to provide a framework for the understanding of the potential molecular mechanisms behind these modulations. Other original aspects of NUTROME will be the evaluation of not only the impact of pure compounds, but also the development of new forms of presenting them (by encapsulation and/or immobilisation) to guarantee that they reach the target site and microbial population of interest in the gut. Collectively this will allow to design nutraceuticals for dietary intervention in the form of enriched foods or dietary supplements. NUTROME provides an exceptional opportunity to the researcher to gain state-of-the-art expertise in microbiomics along with other relevant research and transferable skills to strengthen her competitiveness for becoming an independent researcher.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences nutrition
- natural sciences biological sciences microbiology
- medical and health sciences basic medicine physiology homeostasis
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
T12 YN60 Cork
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.