Objective
Sedimentary ancient DNA (SedaDNA) is DNA associated with non-recent sediments. SedaDNA are found to persist in the environment for geologically relevant timescales and have gained significant popularity for palaeoecological reconstructions and unravelling past biodiversity. Free DNA molecules degrade within days to weeks in the environment due exposure to nucleases, UV radiation, temperature fluctuations and slow spontaneous hydrolysis. The adsorption of DNA to mineral surfaces in sediments appear to preserve DNA molecules, but we do still not understand how mineralogy and soil and sediment conditions affect DNA retention, preservation and recovery. With more quantitative knowledge of DNA-mineral interactions, we can better address the preservation potential in a deposit, unravel the source area of the extracted DNA and develop extraction protocols that provide a higher yield. It is known that the DNA-mineral affinity and adsorption strength vary across mineral and environmental conditions and a strong DNA-mineral association can be speculated to offer a greater preservation potential in contrast to a week DNA-mineral interaction where there would be available bonds for participation in the degradation process. It is also unclear how co-adsorbed biomolecules influence sedaDNA retention and preservation. The aim of MinDNA is to obtain insights into the mechanisms and processes affecting DNA stability on mineral surfaces. MinDNA will take a multidisciplinary approach to obtain quantitative bond parameters, adsorption and degradation measures at the bulk and molecular level as well as performing molecular and bulk level in situ experiments to understand the dynamics of the reactions. Further, the chemistry and nature of the interacting bonds will be quantified using novel FTIR techniques. The gained knowledge will be combined into a conceptual model that can be used by a broad range of researchers to advance the resolution and scope of SedaDNA applications.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences biochemistry biomolecules
- natural sciences biological sciences ecology ecosystems
- natural sciences earth and related environmental sciences geology mineralogy
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1165 KOBENHAVN
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.