Objective
The group of per- and polyfluoroalkyl substances (PFAS) are thermally and chemically stable with strong hydrophobic and lipophobic properties, making them highly suitable for many applications. However, they are part of the emerging chemicals identified to be persistent and bioaccumulative. They are very stable, non-degradable, and present all around the world. More than 9000 distinct individual compounds make up the PFAS group, with a carbon chain backbone between 4 and 14 C atoms in length, and a charged functional moiety: sulfonate or carboxylate. The two principal representatives and studied PFAS (perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS)) are banned in many countries, leading the major global manufacturers to find alternatives having shorter carbon chains (< C8) or with replacement chemistry with multiple ether-oxygens inserted between the perfluorinated carbon backbones, allowing the formation of non-covalent hydrogen bonds with a water molecule, which makes them more labile to degradation. However, those new chemicals have been identified in various environmental matrices are now becoming global contaminants. But our understanding of the PFAS alternatives toxicity is lacking in aquatic organisms and, in the case of emerging replacements and by-products, even not unexplored. Studies assessing their potential genetic, developmental, cellular, and systemic toxicities have not yet been conducted in aquatic organisms. To that purpose, the ECOPFAS project will investigate the acute toxicity, developmental toxicity, genotoxicity and toxicity pathways for PFAS alternatives in three freshwater species. ECOPFAS project will build on the expertise of the researchers involved together with the acquired data to provide a basis for a better understanding of the influence of the effects on individual and population fitness to support a broader integration of these data into risk assessment frameworks.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
4362 Esch Sur Alzette
Luxembourg
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.