Project description
Understanding nutritional metabolomics in early childhood
Childhood obesity is a significant global issue, and effective prevention measures should emphasise the establishment of healthy eating habits and physical activity during childhood. Precision nutrition, utilising metabolomics, tailors prevention and treatment strategies to an individual’s unique characteristics. The MSCA-funded MARCO project will study the metabolomic profiles of children aged 3-6. It explores how eating habits and physical inactivity affect metabolites associated with obesity. Specifically, the project gathers data from a 10-year clinical trial involving multiple centres and a randomised cohort of children. The initial year will concentrate on promoting healthy eating and physical activity. The findings will enhance our understanding of nutritional metabolomics in early childhood, with the goals of preventing childhood obesity and mitigating its impact.
Objective
The high prevalence of childhood obesity in several parts of the world indicates a worrying future health scenario, making prevention
a high priority. This prevention should focus on diet and physical activity. Regarding food, the beginning of establishing eating habits
and preferences occurs in childhood, being necessary that this prevention and treatment is individualized. In this context, precision
nutrition offers a new paradigm for health, where the focus is to prevention and treatment strategies based on an individual's unique
characteristics. Metabolomics (which is in the omics group - transcriptomics, genomics and proteomics) is being considered an
important aspect in precision nutrition, reflecting more realistically effect of food on health and disease. Therefore, the aim of this
project is to identify, the metabolomic profile in children aged 3-6 years, and through a longitudinal intervention, if eating behaviour
and physical inactivity modify the profile of metabolites that can lead to obesity. The data for this proposal will be derived from a
multicenter, parallel, randomized and controlled clinical trial that will be carried out with a cohort of children, followed initially by one
year of intervention, with the intention of 10 years in total. The intervention will be based on healthy eating and physical activity.
Metabolomics data, anthropometric, dietary, socioeconomic, behavioural, metabolic, biochemical and food environment variables
will be collected. Similar studies to this are not available in the literature, and have the potential to increase knowledge about
nutritional metabolomics, especially in early childhood and serve as a database for other studies with this population. This can reduce
childhood obesity, minimize nutritional and metabolic risks in childhood and reduce the economic, environmental and social impact
this disease.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences computer and information sciences databases
- medical and health sciences health sciences nutrition obesity
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
50009 ZARAGOZA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.