Objective
The EU-2030 Biodiversity Strategy (COM/2020/380) aims to ensure Europe’s biodiversity will be on the path to recovery by 2030. Freshwater fish are among the taxa most-threatened by extinction in Europe, with a decline proven in abundance and biomass in most common European freshwater fish species.
For Europe’s biodiversity to be on the path to recovery, researchers, environmental managers and policy makers must identify and mitigate environmental factors and anthropogenic pressures that impact freshwater fish populations.
Chemical pressures are impacting 38% of European surface water. Among the 56 priority hazardous substances monitored in the EU-regulation in surface water, more than one third of them are classified as carcinogenic or suspected to be carcinogenic for humans. These substances may induce embryotoxicity, abnormal development, metabolic disorders and long-term initiation and promotion of carcinogenic pathways in fish species. There is a need to ascertain what ecological risks result from the exposure of aquatic organisms to genotoxicants in the environment, as well as a need to urgently develop innovative diagnostic tools to assess ecological risks in EU surface water.
As proteins play a critical role in tumorigenesis, onco-proteomics has become a growing field in medical cancer research. In this project, we aim to develop next-generation biomarkers for two European endemic freshwater fish species by leveraging emerging high-throughput proteomics methods. Through lab and field experiments, we aim to identify toxicity pathways and relevant biomarkers in fish exposed to genotoxicants as well as relevant biomarker responses that are induced early, before individuals’ survival is threatened. This project will not only pioneer the use of diagnostic tools developed for medical research in the discipline of freshwater fish ecology but will also apply these tools in the field by measuring genotoxicant exposure of native fish populations in the Rhone River basin.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- medical and health sciences clinical medicine oncology
- natural sciences biological sciences ecology ecosystems
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75007 PARIS CEDEX 07
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.