Comprehensive Platform for the Functional Characterization of Cancer Epigenetics and Diagnosis

Project Information

EpiCancer

Grant agreement ID: 101115455

DOI

10.3030/101115455

EC signature date 24 January 2024

Start date 1 February 2024

End date 31 January 2029

Funded under

• European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

WEIZMANN INSTITUTE OF SCIENCE
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer

Author(s): Yael Aylon; Noa Furth; Anna C. Pirona; Adi Lavie; Olga Fedorova; Ori Hassin; Nuno Padrão; Maxime Steinmetz; Avital Sarusi-Potuguez; Liat Fellus-Alyagor; Irit Shimoni; Bareket Dassa; Wilbert Zwart; Efrat Shema; Moshe Oren
Published in: Proceedings of the National Academy of Sciences, 2025, ISSN 1091-6490
Publisher: PNAS
DOI: 10.1073/PNAS.2522646122

Single-molecule systems for the detection and monitoring of plasma-circulating nucleosomes and oncoproteins in diffuse midline glioma

Author(s): Nir Erez, Noa Furth, Vadim Fedyuk, Jack Wadden, Rayan Aittaleb, Tiffany Adam, Kallen Schwark, Michael Niculcea, Madeline Miclea, Rajen Mody, Andrea Franson, Hemant A. Parmar, Mohannad Ibrahim, Benison Lau, Augustine Eze, Niku Nourmohammadi, Iris Fried, Javad Nazarian, Guy Ron, Sriram Venneti, Carl Koschmann, Efrat Shema
Published in: Cell Reports Medicine, Issue 6, 2025, ISSN 2666-3791
Publisher: Elsevier BV
DOI: 10.1016/J.XCRM.2024.101918

Oncogenic IDH1 ^mut drives robust loss of histone acetylation and increases chromatin heterogeneity

Author(s): Noa Furth; Niv Cohen; Avishay Spitzer; Tomer-Meir Salame; Bareket Dassa; Tevie Mehlman; Alexander Brandis; Arieh Moussaieff; Dinorah Friedmann-Morvinski; Maria G. Castro; Jerome Fortin; Mario L. Suvà; Itay Tirosh; Ayelet Erez; Guy Ron; Efrat Shema
Published in: Proceedings of the National Academy of Sciences, 2024, ISSN 1091-6490
Publisher: PNAS
DOI: 10.1073/PNAS.2403862122

Dual targeting of histone deacetylases and MYC as potential treatment strategy for H3-K27M pediatric gliomas

Author(s): Danielle Algranati, Roni Oren, Bareket Dassa, Liat Fellus-Alyagor, Alexander Plotnikov, Haim Barr, Alon Harmelin, Nir London, Guy Ron, Noa Furth, Efrat Shema
Published in: eLife, Issue 13, 2024, ISSN 2050-084X
Publisher: eLife Sciences Publications, Ltd
DOI: 10.7554/ELIFE.96257

PLoS Biology

Author(s): Ofir Griess; Noa Furth; Nofar Harpaz; Nicoletta Di Bernardo; Tomer-Meir Salame; Bareket Dassa; Ioannis Karagiannidis; Yusuke Isshiki; Menachem Gross; Ari M. Melnick; Wendy Béguelin; Guy Ron; Efrat Shema
Published in: PLOS Biology, 2024, ISSN 1544-9173
Publisher: Public Library of Science
DOI: 10.1101/2024.08.05.606629