Project description
Research investigates how the weak force disrupts mirror symmetry of chiral molecules
Molecular chirality is crucial in areas such as drug development, yet fundamental questions surround chiral molecules, especially in relation to why a specific handedness dominates in living systems. Traditionally, the enantiomers of chiral molecules are seen as perfect mirror images, implying easy conversion between them. However, the weak force could violate this parity symmetry in chiral molecules. The ERC-funded Q-ChiMP project seeks to answer whether the weak force matters in chemistry by performing the first trapped chiral molecular ion experiment to measure parity violation. The proposed research will leverage long coherence times of trapped ion experiments to enhance measurement precision. Molecular ion use should also enable generating extended coherence times and high measurement precision. Q-ChiMP results could potentially advance quantum-controlled chemistry and quantum information technology.
Objective
Molecular chirality plays a central role in many fields, ranging from reaction dynamics to drug development. Fundamental questions surround chiral molecules, in particular: Why does a specific handedness prevail in natural living systems? The vast majority of Chemistry textbooks define the two enantiomers of chiral molecules as perfect mirror images, which entails tunnelling conversion between enantiomers. However, a closer look reveals that the non-conservation of spatial inversion exhibited by the weak force should violate the parity symmetry in chiral molecules.
In Q-ChiMP, we aim to answer the fundamental question, Is the weak force important in chemistry? To this end, we will realize the first trapped chiral molecular ion experiment with pristine quantum control to measure parity violation (PV) in molecules for the first time by detecting tiny structural differences between enantiomers. We will use several advantages molecular ions have over neutrals in metrology. First, we will leverage the long coherence times enabled by trapped ion experiments to enhance measurement precision. Second, molecular ions provide a promising path to generate internally cold chiral molecules populating only a few quantum states, which serves as an essential ingredient of precision metrology along with high quantum efficiency in detection. Our main approach to measure PV will use our newly developed vibrational spectroscopy scheme that can extract PV from a racemic sample directly, enhancing measurement precision and overcoming synthesis challenges.
Each of the aims developed in Q-ChiMP toward a measurement of PV serves as an important novel milestone for taming cold polyatomic molecules and can be applied to quantum-controlled chemistry experiments and quantum information technology.
The unique experience of the PI in precision spectroscopy with molecular ion ensembles and experimental cold quantum-controlled chemistry will be instrumental in achieving these ambitious goals.
Fields of science (EuroSciVoc)
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CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
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Programme(s)
- HORIZON.1.1 - European Research Council (ERC) Main Programme
Topic(s)
Funding Scheme
HORIZON-ERC - HORIZON ERC GrantsHost institution
32000 Haifa
Israel