Nanoscintillators to potentiate brain cancer radiotherapy: from physics to preclinical trials

Project Information

RADIANCE

Grant agreement ID: 101116304

DOI

10.3030/101116304

EC signature date 12 September 2023

Start date 1 January 2024

End date 31 December 2028

Funded under

• European Research Council (ERC)

Total cost

€ 1 948 125,00

EU contribution

€ 1 948 125,00

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Physical mechanisms of deep tissue photodynamic therapy using nanoscintillators: A roadmap for designing efficient platforms

Author(s): C. Dujardin, A.-L. Bulin, A. Vasil'ev
Published in: Journal of Luminescence, Issue 289, 2026, ISSN 0022-2313
Publisher: Elsevier BV
DOI: 10.1016/J.JLUMIN.2025.121570

Inorganic Nanoscintillators: Current Trends and Future Perspectives

Author(s): Christophe Dujardin, Aurélie Bessière, Anne‐Laure Bulin, Frédéric Chaput, Benoit Mahler
Published in: Advanced Optical Materials, Issue 13, 2025, ISSN 2195-1071
Publisher: Wiley
DOI: 10.1002/ADOM.202402739

Bioconjugate Chemistry

Author(s): Kristel Bedregal-Portugal; Alexis Mercier; Sarah Stelse-Masson; Clémentine Aubrun; Hélène Elleaume; Camille Verry; Anne-Laure Bulin
Published in: Bioconjugate Chemistry, 2025, ISSN 1043-1802
Publisher: American Chemical Society
DOI: 10.1021/ACS.BIOCONJCHEM.5C00249

Engineering photodynamics for treatment, priming and imaging

Author(s): Obaid, Girgis; Celli, Jonathan; Broekgaarden, Mans; Bulin, Anne-Laure; Uusimaa, Petteri; Pogue, Brian; Hasan, Tayyaba; Huang, Huang-Chiao
Published in: Nature Reviews Bioengineering, 2024, ISSN 2731-6092
Publisher: Springer Nature
DOI: 10.1038/S44222-024-00196-Z

Combined physical and biological contributions to radiotherapy enhancement by Lu-based nanoscintillators in pancreatic cancer models

Author(s): Stelse-Masson, Sarah; Lytvynenko, Xenie; Bedregal-Portugal, Kristel; Aubrun, Clémentine; Lavaud, Matéo; Kadri, Malika; Jacquet, Thibault; Moriscot, Christine; Gallet, Benoit; Chovelon, Benoit; Coll, Jean-Luc; Ravanat, Jean-Luc; Mihóková, Eva; Čuba, Václav; Elleaume, Hélène; Bulin, Anne-Laure
Published in: Nanotheranostics, 2025, ISSN 2206-7418
Publisher: Ivyspring International Publisher
DOI: 10.7150/NTNO.115120

European Journal of Medicinal Chemistry

Author(s): Sofia Leo; Nazareth Milagros Carigga Gutierrez; Anne-Laure Bulin; Jean-Luc Coll; Lucie Sancey; Benoit Habermeyer; Mans Broekgaarden
Published in: European Journal of Medicinal Chemistry, 2025, ISSN 0223-5234
Publisher: Elsevier
DOI: 10.1016/J.EJMECH.2025.117861

Monomer Versus Dimer of Cationic Ir(III) Complexes for Photodynamic Therapy by Two-Photon Activation: A Comparative Study

Author(s): Barta, Agoston; Vanwonterghem, Laetitia; Lavaud, Matéo; Molton, Florian; Micouin, Guillaume; Bulin, Anne-Laure; Banyasz, A.; Coll, Jean-Luc; Loiseau, Frédérique; Hurbin, Amandine; Lanoë, Pierre-Henri
Published in: ACS Applied Bio Materials, 2025, ISSN 2576-6422
Publisher: American Chemical Society
DOI: 10.1021/ACSABM.5C00393

Advanced Materials

Author(s): Carigga Gutierrez, Nazareth Milagros; Clainche, Tristan Le; Bulin, Anne‐laure; Leo, Sofia; Kadri, Malika; Abdelhamid, Ahmed Gamal Ali; Pujol-Solé, Núria; Obaid, Girgis; Hograindleur, Marc‐andré; Gardette, Vincent; Busser, Benoit; Motto-Ros, Vincent; Josserand, Véronique; Henry, Maxime; Sancey, Lucie; Hurbin, Amandine; Elleaume, Hélène; Kandiah, Eaazhisai; Guével, Xavier Le; Coll, Jean‐luc; Broekgaarden, Mans
Published in: Advanced Materials, 2024, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/ADMA.202404605

Nanoscintillator Coating: A Key Parameter That Strongly Impacts Internalization, Biocompatibility, and Therapeutic Efficacy in Pancreatic Cancer Models

Author(s): Aubrun Fulbert, Clémentine; Chaput, Fréderic; Stelse-Masson, Sarah; Henry, Maxime; Chovelon, Benoit; Bohic, Sylvain; Brueckner, Dennis; Garrevoet, Jan; Moriscot, Christine; Gallet, Benoit; Vollaire, Julien; Nicoud, Olivier; Lerouge, Frédéric; Denis-Quanquin, Sandrine; Jaurand, Xavier; Jacquet, Thibault; Nomezine, Anthony; Josserand, Véronique; Coll, Jean‐luc; Ravanat, Jean‐luc; Elleaume, Hélène; Bulin, Anne‐laure
Published in: Small Science, 2024, ISSN 2688-4046
Publisher: John Wiley & Sons, Ltd
DOI: 10.3204/PUBDB-2024-06973

The role of energy deposition on the luminescence sensitization in porphyrin-functionalized SiO₂/ZnO nanoparticles under X-ray excitation

Author(s): Villa I.; Crapanzano R.; Mostoni S.; Bulin A. -L.; D'Arienzo M.; Di Credico B.; Vedda A.; Scotti R.; Fasoli M.
Published in: Nanoscale Advances, 2025, ISSN 2516-0230
Publisher: Royal Society of Chemistry
DOI: 10.1039/D4NA00640B

Cationic iridium( <scp>iii</scp> ) complexes with a halogen-substituted pyridylbenzimidazole ancillary ligand for photodynamic therapy

Author(s): Pierre-Henri Lanoë, Frédérique Loiseau, Christian Philouze, Camille Latouche, Laetitia Vanwonterghem, Louis Biancon, Ahmed S. Faihan, Florian Molton, Matéo Lavaud, Anne-Laure Bulin, Jean-Luc Coll, Akos Banyasz, Amandine Hurbin
Published in: Materials Advances, Issue 6, 2025, ISSN 2633-5409
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5MA00964B