Patient-specific Microstructural and radIobiological model for persoNalised external beam radiatIONn therapy in localised tumourS

Project Information

MINIONS

Grant agreement ID: 101116811

DOI

10.3030/101116811

EC signature date 15 April 2024

Start date 1 September 2024

End date 31 August 2029

Funded under

• European Research Council (ERC)

Total cost

€ 1 487 676,00

EU contribution

€ 1 487 676,00

Coordinated by

POLITECNICO DI MILANO
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Microstructural profiling and habitat analysis to characterize treatment outcome patterns in Sacral Chordomas treated with carbon ions

Author(s): Letizia Morelli, Giovanni Parrella, Marco Rotondi, Silvia Molinelli, Giuseppe Magro, Sara Imparato, Agnieszka Chalaszczyk, Maria Rosaria Fiore, Chiara Paganelli, Ester Orlandi, Guido Baroni
Published in: Medical Physics, Issue 53, 2026, ISSN 0094-2405
Publisher: Wiley
DOI: 10.1002/MP.70208

Microstructural modelling based on diffusion weighted imaging to guide dose painting in carbon ions for large sacral chordomas

Author(s): Giovanni Parrella, Letizia Morelli, Giuseppe Magro, Lars Glimelius, Jakob Ödén, Mario Ciocca, Sara Imparato, Marco Rotondi, Maria Rosaria Fiore, Ester Orlandi, Guido Baroni, Silvia Molinelli, Chiara Paganelli
Published in: Physics and Imaging in Radiation Oncology, Issue 36, 2025, ISSN 2405-6316
Publisher: Elsevier BV
DOI: 10.1016/J.PHRO.2025.100887

Evaluating the technical feasibility of biology-guided dose painting in proton therapy

Author(s): Caterina Brighi, Giovanni Parrella, Letizia Morelli, Silvia Molinelli, Giuseppe Magro, Sara Lillo, Alberto Iannalfi, Mario Ciocca, Sara Imparato, David E.J. Waddington, Paul Keall, Chiara Paganelli, Ester Orlandi, Guido Baroni
Published in: Physics and Imaging in Radiation Oncology, Issue 35, 2025, ISSN 2405-6316
Publisher: Elsevier BV
DOI: 10.1016/J.PHRO.2025.100832

Machine Learning-Based Extraction of Microstructural Parameters from Diffusion-Weighted Imaging starting from realistic in silico cellular substrates: application in breast and prostate cancer

Author(s): Chiara Tinelli, Chiara Scotti, Fabio Casaccio, Marko Zlatic, Guido Baroni, Letizia Morelli, Chiara Paganelli
Published in: Computer Methods and Programs in Biomedicine, 2026, ISSN 0169-2607
Publisher: Elsevier BV
DOI: 10.1016/J.CMPB.2026.109551

Quantitative Susceptibility Mapping in Skull Base Chordoma: In Silico Analysis and In Vivo Application Towards Indirect Hypoxia Assessment

Author(s): P. Fenech, L. Morelli, G. Parrella, S. Imparato, A. Iannalfi, S. Lillo, E. Orlandi, G. Baroni, C. Paganelli
Published in: Magnetic Resonance in Medicine, Issue 95, 2026, ISSN 0740-3194
Publisher: Wiley
DOI: 10.1002/MRM.70193

Tumor control probability in large sacral chordomas treated with carbon ions radiotherapy integrating advanced microstructural modelling

Author(s): Giovanni Parrella, Letizia Morelli, Silvia Molinelli, Giuseppe Magro, Lars Glimelius, Jakob Ödén, Mario Ciocca, Sara Imparato, Marco Rotondi, Maria Rosaria Fiore, Ester Orlandi, Guido Baroni, Chiara Paganelli
Published in: Physica Medica, Issue 136, 2025, ISSN 1120-1797
Publisher: Elsevier BV
DOI: 10.1016/J.EJMP.2025.105038